Mechanism of heart-rate turbulence

Recently, two post-myocardial-infarction risk predictors were introduced that are superior to all other presently available indicators: turbulence onset (TO) and turbulence slope (TS). These new parameters characterize the behavior of instantaneous heart rate after a ventricular premature beat (VPB)...

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Bibliographic Details
Main Authors: Mrowka, R., Persson, P.B., Theres, H., Patzak, A.
Format: Conference Proceeding
Language:English
Subjects:
Baroreflex
Cardiology
Frequency
Heart rate
Heart rate variability
Hemodynamics
Mathematical model
Oscillators
Pacemakers
Rhythm
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Summary:Recently, two post-myocardial-infarction risk predictors were introduced that are superior to all other presently available indicators: turbulence onset (TO) and turbulence slope (TS). These new parameters characterize the behavior of instantaneous heart rate after a ventricular premature beat (VPB), i.e., they describe the reestablishing of heart rate control after an acute perturbation. We propose that the dysfunction of an important cardiovascular control mechanism-the arterial baroreflex-is the mechanism behind these new potent markers. The hypothesis is tested by means of a mathematical model. The results of the model indicates that the recently established risk parameters TO and TS characterize baroreflex function, a known risk stratifier in patients.
ISSN:0276-6547
DOI:10.1109/CIC.2000.898553