The Study of Three-dimensional Tissue-engineering Structures Obtained Using Laser Printing for Muscle Regeneration

The aim of this work is an in vivo study of the biocompatibility of samples of three-dimensional tissue-engineering structures for of muscle tissue regeneration. Three-dimensional tissue-engineering structures were formed by layer-by-layer deposition of dispersions of albumin, collagen, chitosan wit...

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Bibliographic Details
Main Authors: Demidenko, Natalia, Cherepanova, Nadezda, Semak, Anna, Bychkov, Vladislav, Komarchev, Alexey
Format: Conference Proceeding
Language:English
Subjects:
3d printing
Birds
Carbon nanotubes
cells and tissue-engineering
Connective tissue
laser
Lasers
muscle regeneration
Muscles
Proteins
Substrates
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Summary:The aim of this work is an in vivo study of the biocompatibility of samples of three-dimensional tissue-engineering structures for of muscle tissue regeneration. Three-dimensional tissue-engineering structures were formed by layer-by-layer deposition of dispersions of albumin, collagen, chitosan with carbon nanotubes using laser printing. Under the action of laser radiation, carbon nanotubes oriented into a conducting scaffold. During implantation of tissue-engineering constructions, no toxic effects were revealed to laboratory birds. Studies have shown that carbon nanotubes do not have a pathological effect on the morphology of living cells and tissues, also enhance the proliferation of fibroblasts and stimulate the growth of connective and muscle tissue.
ISSN:2376-6565
DOI:10.1109/EIConRus49466.2020.9039285