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Neuro-electronic devices and nanotools to interact with neuronal networks
Neuro-electronic interfaces play a fundamental role for studying brain functions and cellular mechanisms of information processing both in vitro and in vivo. Here we present a new concept in which electronic devices are integrated with models of neuronal networks of human origin together with nanoto...
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| container_end_page | 14.1.4 |
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| creator | Martinoia, S. Andolfi, A. Muzzi, L. Pisano, M. Spanu, A. Raiteri, R. |
| description | Neuro-electronic interfaces play a fundamental role for studying brain functions and cellular mechanisms of information processing both in vitro and in vivo. Here we present a new concept in which electronic devices are integrated with models of neuronal networks of human origin together with nanotools to characterize the (patho)physiology of such in vitro complex systems. Large-scale CMOS micro-transducer arrays, coupled to 2D and 3D networks are presented together with new techniques for non-invasively modulate the cell activity. Specifically, piezo-electric nano particles and gold nano rods are used to excite-inhibit the neural activity that is recorded by the micro-transducer arrays. Concept, technology, and preliminary results are presented toward the implementation of a bio-hybrid brain-on-a-chip. |
| doi_str_mv | 10.1109/IEDM13553.2020.9372044 |
| format | conference_proceeding |
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| fulltext | fulltext_linktorsrc |
| identifier | EISSN: 2156-017X |
| ispartof | 2020 IEEE International Electron Devices Meeting (IEDM), 2020, p.14.1.1-14.1.4 |
| issn | 2156-017X |
| language | eng |
| recordid | cdi_ieee_primary_9372044 |
| source | IEEE Xplore All Conference Series |
| subjects | Biological neural networks In vitro Nanoscale devices Neural activity Semiconductor device modeling Three-dimensional displays Two dimensional displays |
| title | Neuro-electronic devices and nanotools to interact with neuronal networks |
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