Cotinine and IL-6 - Biomarkers for Estimating Pharmacological Processes in Various Forms of Periodontitis

Prunus spinosa L. is a medicinal plant found in the flora of many countries, especially in Central and Eastern Europe, being used for various pharmacological actions. In this study, the antioxidant properties of the species were evaluated on specific salivary biomarkers, in healthy volunteers, smoke...

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Main Authors: Mitea, Gabriela, Iancu, Irina Mihaela, Blebea, Nicoleta Mirela, Bucur, Laura Adriana, Schroder, Verginica, Badea, Victoria, Badea, Ciprian Florin, Nuca, Cristina, Radu, Marius Daniel, Iancu, Valeriu
Format: Conference Proceeding
Language:English
Subjects:
antioxidants
aqueous extract
Biomarkers
Biomedical engineering
Diseases
Europe
Indexes
periodontal disease
Pharmaceuticals
pharmacological processes
Sensitivity
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Summary:Prunus spinosa L. is a medicinal plant found in the flora of many countries, especially in Central and Eastern Europe, being used for various pharmacological actions. In this study, the antioxidant properties of the species were evaluated on specific salivary biomarkers, in healthy volunteers, smokers and non-smokers, but also in subjects with periodontal disease using an aqueous extract obtained from the dried fruits of the harvested species from Tulcea County, Romania. The results obtained show that, regarding the two evaluated markers, cotinine and salivary interleukin 6 in groups of patients with superficial and deep chronic periodontal disease can serve as tools for evaluating the potential therapeutic effect of Prunus spinosa L. extract in the periodontal disease.
ISSN:2575-5145
DOI:10.1109/EHB52898.2021.9657536