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A Thin Transducer With Integrated Acoustic Metamaterial for Cardiac CT Imaging and Gating
Coronary artery disease (CAD) is a leading cause of death globally. Computed tomography coronary angiography (CTCA) is a noninvasive imaging procedure for diagnosis of CAD. However, CTCA requires cardiac gating to ensure that diagnostic-quality images are acquired in all patients. Gating reliability...
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Published in: | IEEE transactions on ultrasonics, ferroelectrics, and frequency control ferroelectrics, and frequency control, 2022-03, Vol.69 (3), p.1064-1076 |
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description | Coronary artery disease (CAD) is a leading cause of death globally. Computed tomography coronary angiography (CTCA) is a noninvasive imaging procedure for diagnosis of CAD. However, CTCA requires cardiac gating to ensure that diagnostic-quality images are acquired in all patients. Gating reliability could be improved by utilizing ultrasound (US) to provide a direct measurement of cardiac motion; however, commercially available US transducers are not computed tomography (CT) compatible. To address this challenge, a CT-compatible 2.5-MHz cardiac phased array transducer is developed via modeling, and then, an initial prototype is fabricated and evaluated for acoustic and radiographic performance. This 92-element piezoelectric array transducer is designed with a thin acoustic backing (6.5 mm) to reduce the volume of the radiopaque acoustic backing that typically causes arrays to be incompatible with CT imaging. This thin acoustic backing contains two rows of air-filled, triangular prism-shaped voids that operate as an acoustic diode. The developed transducer has a bandwidth of 50% and a single-element SNR of 9.9 dB compared to 46% and 14.7 dB for a reference array without an acoustic diode. In addition, the acoustic diode reduces the time-averaged reflected acoustic intensity from the back wall of the acoustic backing by 69% compared to an acoustic backing of the same composition and thickness without the acoustic diode. The feasibility of real-time echocardiography using this array is demonstrated in vivo , including the ability to image the position of the interventricular septum, which has been demonstrated to effectively predict cardiac motion for prospective, low radiation CTCA gating. |
doi_str_mv | 10.1109/TUFFC.2021.3140034 |
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Computed tomography coronary angiography (CTCA) is a noninvasive imaging procedure for diagnosis of CAD. However, CTCA requires cardiac gating to ensure that diagnostic-quality images are acquired in all patients. Gating reliability could be improved by utilizing ultrasound (US) to provide a direct measurement of cardiac motion; however, commercially available US transducers are not computed tomography (CT) compatible. To address this challenge, a CT-compatible 2.5-MHz cardiac phased array transducer is developed via modeling, and then, an initial prototype is fabricated and evaluated for acoustic and radiographic performance. This 92-element piezoelectric array transducer is designed with a thin acoustic backing (6.5 mm) to reduce the volume of the radiopaque acoustic backing that typically causes arrays to be incompatible with CT imaging. This thin acoustic backing contains two rows of air-filled, triangular prism-shaped voids that operate as an acoustic diode. The developed transducer has a bandwidth of 50% and a single-element SNR of 9.9 dB compared to 46% and 14.7 dB for a reference array without an acoustic diode. In addition, the acoustic diode reduces the time-averaged reflected acoustic intensity from the back wall of the acoustic backing by 69% compared to an acoustic backing of the same composition and thickness without the acoustic diode. The feasibility of real-time echocardiography using this array is demonstrated in vivo , including the ability to image the position of the interventricular septum, which has been demonstrated to effectively predict cardiac motion for prospective, low radiation CTCA gating.</description><identifier>ISSN: 0885-3010</identifier><identifier>EISSN: 1525-8955</identifier><identifier>DOI: 10.1109/TUFFC.2021.3140034</identifier><identifier>PMID: 34971531</identifier><identifier>CODEN: ITUCER</identifier><language>eng</language><publisher>United States: IEEE</publisher><subject>Acoustic arrays ; Acoustic diode ; acoustic metamaterial ; Acoustics ; Angiography ; Cardiovascular disease ; Computed tomography ; computed tomography (CT) ; computed tomography coronary angiography (CTCA) ; Coronary artery disease ; CT-compatible transducer ; Echocardiography ; Equipment Design ; Humans ; Image acquisition ; Image quality ; Imaging ; Medical imaging ; Metamaterials ; Phased arrays ; Piezoelectricity ; Prospective Studies ; Reflection ; Reproducibility of Results ; Septum ; Tomography ; Tomography, X-Ray Computed ; Transducers ; Ultrasonic imaging</subject><ispartof>IEEE transactions on ultrasonics, ferroelectrics, and frequency control, 2022-03, Vol.69 (3), p.1064-1076</ispartof><rights>Copyright The Institute of Electrical and Electronics Engineers, Inc. (IEEE) 2022</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c395t-a3bc5754a7b987d0379a65a87f89dd16ceac10240e9bd9ff0a55f0a9cf83ddfc3</citedby><cites>FETCH-LOGICAL-c395t-a3bc5754a7b987d0379a65a87f89dd16ceac10240e9bd9ff0a55f0a9cf83ddfc3</cites><orcidid>0000-0003-3426-367X ; 0000-0001-6474-3194 ; 0000-0001-7128-108X</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://ieeexplore.ieee.org/document/9667383$$EHTML$$P50$$Gieee$$H</linktohtml><link.rule.ids>314,780,784,27924,27925,54796</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/34971531$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Rojas, Stephan Strassle</creatorcontrib><creatorcontrib>Tridandapani, Srini</creatorcontrib><creatorcontrib>Lindsey, Brooks D.</creatorcontrib><title>A Thin Transducer With Integrated Acoustic Metamaterial for Cardiac CT Imaging and Gating</title><title>IEEE transactions on ultrasonics, ferroelectrics, and frequency control</title><addtitle>T-UFFC</addtitle><addtitle>IEEE Trans Ultrason Ferroelectr Freq Control</addtitle><description>Coronary artery disease (CAD) is a leading cause of death globally. Computed tomography coronary angiography (CTCA) is a noninvasive imaging procedure for diagnosis of CAD. However, CTCA requires cardiac gating to ensure that diagnostic-quality images are acquired in all patients. Gating reliability could be improved by utilizing ultrasound (US) to provide a direct measurement of cardiac motion; however, commercially available US transducers are not computed tomography (CT) compatible. To address this challenge, a CT-compatible 2.5-MHz cardiac phased array transducer is developed via modeling, and then, an initial prototype is fabricated and evaluated for acoustic and radiographic performance. This 92-element piezoelectric array transducer is designed with a thin acoustic backing (6.5 mm) to reduce the volume of the radiopaque acoustic backing that typically causes arrays to be incompatible with CT imaging. This thin acoustic backing contains two rows of air-filled, triangular prism-shaped voids that operate as an acoustic diode. The developed transducer has a bandwidth of 50% and a single-element SNR of 9.9 dB compared to 46% and 14.7 dB for a reference array without an acoustic diode. In addition, the acoustic diode reduces the time-averaged reflected acoustic intensity from the back wall of the acoustic backing by 69% compared to an acoustic backing of the same composition and thickness without the acoustic diode. The feasibility of real-time echocardiography using this array is demonstrated in vivo , including the ability to image the position of the interventricular septum, which has been demonstrated to effectively predict cardiac motion for prospective, low radiation CTCA gating.</description><subject>Acoustic arrays</subject><subject>Acoustic diode</subject><subject>acoustic metamaterial</subject><subject>Acoustics</subject><subject>Angiography</subject><subject>Cardiovascular disease</subject><subject>Computed tomography</subject><subject>computed tomography (CT)</subject><subject>computed tomography coronary angiography (CTCA)</subject><subject>Coronary artery disease</subject><subject>CT-compatible transducer</subject><subject>Echocardiography</subject><subject>Equipment Design</subject><subject>Humans</subject><subject>Image acquisition</subject><subject>Image quality</subject><subject>Imaging</subject><subject>Medical imaging</subject><subject>Metamaterials</subject><subject>Phased arrays</subject><subject>Piezoelectricity</subject><subject>Prospective Studies</subject><subject>Reflection</subject><subject>Reproducibility of Results</subject><subject>Septum</subject><subject>Tomography</subject><subject>Tomography, X-Ray Computed</subject><subject>Transducers</subject><subject>Ultrasonic imaging</subject><issn>0885-3010</issn><issn>1525-8955</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2022</creationdate><recordtype>article</recordtype><recordid>eNpdkEtPwzAMgCMEgvH4AyChSFy4dOTZJsepYjAJxKUIcaq8JB1BawtJe-Dfk7HBgYtt2Z8t60PonJIppUTfVM_zeTllhNEpp4IQLvbQhEomM6Wl3EcTopTMOKHkCB3H-E4IFUKzQ3TEhS6o5HSCXme4evMdrgJ00Y7GBfzihze86Aa3CjA4i2emH-PgDX50A7SpFTyscdMHXEKwHgwuK7xoYeW7FYbO4jsYUnmKDhpYR3e2yyfoeX5blffZw9Pdopw9ZIZrOWTAl0YWUkCx1KqwhBcacgmqaJS2lubGgaGECeL00uqmISBlCto0ilvbGH6Crrd3P0L_Obo41K2Pxq3X0Ln0eM1yKjVjuhAJvfqHvvdj6NJ3ieKSCKmoThTbUib0MQbX1B_BtxC-akrqjfj6R3y9EV_vxKely93pcdk6-7fyazoBF1vAO-f-xjrPC644_wY-xoZL</recordid><startdate>20220301</startdate><enddate>20220301</enddate><creator>Rojas, Stephan Strassle</creator><creator>Tridandapani, Srini</creator><creator>Lindsey, Brooks D.</creator><general>IEEE</general><general>The Institute of Electrical and Electronics Engineers, Inc. (IEEE)</general><scope>97E</scope><scope>RIA</scope><scope>RIE</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7SP</scope><scope>7U5</scope><scope>8FD</scope><scope>F28</scope><scope>FR3</scope><scope>L7M</scope><scope>7X8</scope><orcidid>https://orcid.org/0000-0003-3426-367X</orcidid><orcidid>https://orcid.org/0000-0001-6474-3194</orcidid><orcidid>https://orcid.org/0000-0001-7128-108X</orcidid></search><sort><creationdate>20220301</creationdate><title>A Thin Transducer With Integrated Acoustic Metamaterial for Cardiac CT Imaging and Gating</title><author>Rojas, Stephan Strassle ; Tridandapani, Srini ; Lindsey, Brooks D.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c395t-a3bc5754a7b987d0379a65a87f89dd16ceac10240e9bd9ff0a55f0a9cf83ddfc3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2022</creationdate><topic>Acoustic arrays</topic><topic>Acoustic diode</topic><topic>acoustic metamaterial</topic><topic>Acoustics</topic><topic>Angiography</topic><topic>Cardiovascular disease</topic><topic>Computed tomography</topic><topic>computed tomography (CT)</topic><topic>computed tomography coronary angiography (CTCA)</topic><topic>Coronary artery disease</topic><topic>CT-compatible transducer</topic><topic>Echocardiography</topic><topic>Equipment Design</topic><topic>Humans</topic><topic>Image acquisition</topic><topic>Image quality</topic><topic>Imaging</topic><topic>Medical imaging</topic><topic>Metamaterials</topic><topic>Phased arrays</topic><topic>Piezoelectricity</topic><topic>Prospective Studies</topic><topic>Reflection</topic><topic>Reproducibility of Results</topic><topic>Septum</topic><topic>Tomography</topic><topic>Tomography, X-Ray Computed</topic><topic>Transducers</topic><topic>Ultrasonic imaging</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Rojas, Stephan Strassle</creatorcontrib><creatorcontrib>Tridandapani, Srini</creatorcontrib><creatorcontrib>Lindsey, Brooks D.</creatorcontrib><collection>IEEE All-Society Periodicals Package (ASPP) 2005-present</collection><collection>IEEE All-Society Periodicals Package (ASPP) 1998-Present</collection><collection>IEEE Xplore</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Electronics & Communications Abstracts</collection><collection>Solid State and Superconductivity Abstracts</collection><collection>Technology Research Database</collection><collection>ANTE: Abstracts in New Technology & Engineering</collection><collection>Engineering Research Database</collection><collection>Advanced Technologies Database with Aerospace</collection><collection>MEDLINE - Academic</collection><jtitle>IEEE transactions on ultrasonics, ferroelectrics, and frequency control</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Rojas, Stephan Strassle</au><au>Tridandapani, Srini</au><au>Lindsey, Brooks D.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>A Thin Transducer With Integrated Acoustic Metamaterial for Cardiac CT Imaging and Gating</atitle><jtitle>IEEE transactions on ultrasonics, ferroelectrics, and frequency control</jtitle><stitle>T-UFFC</stitle><addtitle>IEEE Trans Ultrason Ferroelectr Freq Control</addtitle><date>2022-03-01</date><risdate>2022</risdate><volume>69</volume><issue>3</issue><spage>1064</spage><epage>1076</epage><pages>1064-1076</pages><issn>0885-3010</issn><eissn>1525-8955</eissn><coden>ITUCER</coden><abstract>Coronary artery disease (CAD) is a leading cause of death globally. Computed tomography coronary angiography (CTCA) is a noninvasive imaging procedure for diagnosis of CAD. However, CTCA requires cardiac gating to ensure that diagnostic-quality images are acquired in all patients. Gating reliability could be improved by utilizing ultrasound (US) to provide a direct measurement of cardiac motion; however, commercially available US transducers are not computed tomography (CT) compatible. To address this challenge, a CT-compatible 2.5-MHz cardiac phased array transducer is developed via modeling, and then, an initial prototype is fabricated and evaluated for acoustic and radiographic performance. This 92-element piezoelectric array transducer is designed with a thin acoustic backing (6.5 mm) to reduce the volume of the radiopaque acoustic backing that typically causes arrays to be incompatible with CT imaging. This thin acoustic backing contains two rows of air-filled, triangular prism-shaped voids that operate as an acoustic diode. The developed transducer has a bandwidth of 50% and a single-element SNR of 9.9 dB compared to 46% and 14.7 dB for a reference array without an acoustic diode. In addition, the acoustic diode reduces the time-averaged reflected acoustic intensity from the back wall of the acoustic backing by 69% compared to an acoustic backing of the same composition and thickness without the acoustic diode. 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subjects | Acoustic arrays Acoustic diode acoustic metamaterial Acoustics Angiography Cardiovascular disease Computed tomography computed tomography (CT) computed tomography coronary angiography (CTCA) Coronary artery disease CT-compatible transducer Echocardiography Equipment Design Humans Image acquisition Image quality Imaging Medical imaging Metamaterials Phased arrays Piezoelectricity Prospective Studies Reflection Reproducibility of Results Septum Tomography Tomography, X-Ray Computed Transducers Ultrasonic imaging |
title | A Thin Transducer With Integrated Acoustic Metamaterial for Cardiac CT Imaging and Gating |
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