Generative DNA: Representation Learning for DNA-based Approximate Image Storage

• Main Authors: Franzese, Giulio, Yan, Yiqing, Serra, Giuseppe, D'Onofrio, Ivan, Appuswamy, Raja, Michiardi, Pietro
• Format: Conference Proceeding
• Language: English
• Subjects: approxi-mate storage; compression; Costs; DNA; DNA storage; Image coding; Representation learning; Roads; Sequential analysis; Visual communication
• ISSN: 2642-9357
• DOI: 10.1109/VCIP53242.2021.9675366

Synthetic DNA has received much attention recently as a long-term archival medium alternative due to its high density and durability characteristics. However, most current work has primarily focused on using DNA as a precise storage medium. In this work, we take an alternate view of DNA. Using neural-network-based compression techniques, we transform images into a latent-space representation, which we then store on DNA. By doing so, we transform DNA into an approximate image storage medium, as images generated back from DNA are only approximate representations of the original images. Using several datasets, we investigate the storage benefits of approximation, and study the impact of DNA storage errors (substitutions, indels, bias) on the quality of approximation. In doing so, we demonstrate the feasibility and potential of viewing DNA as an approximate storage medium.