Nucleosides analogues recognition by molecularly imprinted polymer-coated Love wave sensor

Presented is a process for thin film molecularly imprinted polymer (MIP) coating based on commercial nucleotides adenosine monophosphate (AMP). The compatibility of the MIP film with acoustic propagation and sensor sensitivity for rebinding of AMP have been verified. Thin and porous layers of AMP-ba...

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Bibliographic Details
Published in:Micro & nano letters 2013-10, Vol.8 (10), p.563-566
Main Authors: Lebal, N, Hallil, H, Dejous, C, Plano, B, Krstulja, A, Delepée, R, Agrofoglio, L, Rebière, D
Format: Article
Language:English
Subjects:
acoustic devices
Acoustic propagation
acoustic sensor
acoustic wave propagation
Adenosine monophosphate
AMP concentration
AMP rebinding
AMP‐based MIP layers
aqueous media
biomedical equipment
coatings
Deposition
Engineering Sciences
Extraction
Love waves
Micro and nanotechnologies
Microelectronics
MIP film
molecularly imprinted polymer‐coated Love wave sensor
Nucleosides
Nucleotides
polymer films
porous layers
porous materials
rebinding capacity
Sensors
Special Section: Expanded Papers from NEMS 2013
thin film sensors
Thin films
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Summary:Presented is a process for thin film molecularly imprinted polymer (MIP) coating based on commercial nucleotides adenosine monophosphate (AMP). The compatibility of the MIP film with acoustic propagation and sensor sensitivity for rebinding of AMP have been verified. Thin and porous layers of AMP-based MIP layers were successfully deposited on the sensor surface. Detection tests of AMP have been performed in aqueous media. The sensor response was recorded in terms of frequency and total insertion losses after both steps: AMP extraction from MIP then AMP rebinding. The sensor showed high sensitivity to 25 ppm AMP concentration. The effect of the extraction time on rebinding capacity of the MIP layer has been proven.
ISSN:1750-0443
1750-0443
DOI:10.1049/mnl.2013.0207