Development and characterisation of glucosamine sulphate magnetic nanoparticles for rheumatoid arthritis chemotherapy

Rheumatoid arthritis (RA) is an autoimmune disease that principally attacks synovial joints. RA also cause inflammation in the joints and associated regions. There is an unmet medical need for RA as well as for the targetted drug delivery of anti-rheumatic drugs to improve its efficacy at a much low...

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Bibliographic Details
Published in:Micro & nano letters 2020-11, Vol.15 (13), p.954-958
Main Authors: Subbiah, Latha, Palanisamy, Selvamani, Thimiri Govinda Raj, Deepak B
Format: Article
Language:English
Subjects:
anti‐rheumatic drugs
Arthritis
associated regions
autoimmune disease
Autoimmune diseases
biochemistry
biomedical materials
cancer
cellular biophysics
Chemotherapy
diseases
Drug delivery systems
drugs
glucosamine sulphate magnetic nanoparticles
Joints (anatomy)
magnetic particles
magnetically targetted RA chemotherapy
molecular biophysics
nanomedicine
Nanoparticles
patient treatment
Rheumatoid arthritis
rheumatoid arthritis chemotherapy
Side effects
Synovial joints
targetted drug delivery
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Summary:Rheumatoid arthritis (RA) is an autoimmune disease that principally attacks synovial joints. RA also cause inflammation in the joints and associated regions. There is an unmet medical need for RA as well as for the targetted drug delivery of anti-rheumatic drugs to improve its efficacy at a much lower doses while decreasing its side effects. Hence, in this Letter, the authors report the development and characterisation of glucosamine sulphate magnetic nanoparticles for magnetically targetted RA chemotherapy.
ISSN:1750-0443
1750-0443
DOI:10.1049/mnl.2019.0748