Tuberculous Pancreatic Abscess in an HIV Antibody-negative Patient: Case Report and Review

Tuberculosis (TB) is most commonly diagnosed as a pulmonary disease; however, haematogenous spread of the organism can cause disease in any organ system. We report the case of a 30-y-old woman, Human Immunodeficiency Virus (HIV) antibody-negative, who was diagnosed as having a pancreatic mass on com...

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Bibliographic Details
Published in:Scandinavian journal of infectious diseases 1998, Vol.30 (2), p.99-104
Main Authors: JENNEY, A. W. J, PICKLES, R. W, HELLARD, M. E, SPELMAN, D. W, FULLER, A. J, SPICER, W. J
Format: Article
Language:English
Subjects:
Abdominal Abscess - diagnosis
Abdominal Abscess - physiopathology
Abdominal Abscess - therapy
Adult
AIDS/HIV
Antitubercular Agents - therapeutic use
Bacterial diseases
Biological and medical sciences
Female
Follow-Up Studies
HIV Seronegativity
Human bacterial diseases
Human immunodeficiency virus 1
Humans
Infectious diseases
Laparotomy - methods
Medical sciences
Mycobacterium tuberculosis
Mycobacterium tuberculosis - isolation & purification
Pancreatic Diseases - diagnosis
Pancreatic Diseases - physiopathology
Pancreatic Diseases - therapy
Tomography, X-Ray Computed
Tuberculosis and atypical mycobacterial infections
Tuberculosis, Endocrine - diagnosis
Tuberculosis, Endocrine - physiopathology
Tuberculosis, Endocrine - therapy
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Summary:Tuberculosis (TB) is most commonly diagnosed as a pulmonary disease; however, haematogenous spread of the organism can cause disease in any organ system. We report the case of a 30-y-old woman, Human Immunodeficiency Virus (HIV) antibody-negative, who was diagnosed as having a pancreatic mass on computed tomographic (CT) scans. She underwent a laparotomy and the fluid drained from the mass was culture-positive for Mycobacterium tuberculosis. We review the clinical details of 37 similar cases of pancreatic TB in the literature, where each patient's HIV antibody status is negative or unknown. In this series 3 patients died (1 of these had commenced anti-TB therapy, the others had not) but the remaining 34 responded well to radiological-guided drainage and/or surgical intervention and anti-TB therapy. TB should be considered in the differential diagnosis of a pancreatic mass, especially when associated with epigastric pain or discomfort and weight loss.
ISSN:0036-5548
1651-1980
DOI:10.1080/003655498750003438