Sympathetic Ophthalmia Following Vitrectomy for Endophthalmitis After Intravitreal Bevacizumab

Purpose: To describe a case of sympathetic ophthalmia following vitrectomy for endophthalmitis after an intravitreal injection of bevacizumab. Design: Retrospective case report. Methods: An 84-year-old male developed sympathetic ophthalmia 4 months after vitrectomy for endophthalmitis following an i...

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Bibliographic Details
Published in:Ocular immunology and inflammation 2008-01, Vol.16 (5-6), p.236-238
Main Authors: Sisk, Robert A., Davis, Janet L., Dubovy, Sander R., Smiddy, William E.
Format: Article
Language:English
Subjects:
Administration, Oral
Aged, 80 and over
Anti-Inflammatory Agents - administration & dosage
Antibodies, Monoclonal - administration & dosage
Antibodies, Monoclonal, Humanized
Azathioprine - administration & dosage
Bevacizumab
Drug Therapy, Combination
endophthalmitis
Endophthalmitis - surgery
Eye Enucleation
Humans
Injections
intravitreal bevacizumab
Male
Ophthalmia, Sympathetic - etiology
Ophthalmia, Sympathetic - pathology
Ophthalmia, Sympathetic - physiopathology
Ophthalmia, Sympathetic - surgery
phacoanaphylactic endophthalmitis
Postoperative Complications
Prednisone - administration & dosage
Retrospective Studies
sympathetic ophthalmia
Visual Acuity
Vitrectomy
Vitreous Body
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Summary:Purpose: To describe a case of sympathetic ophthalmia following vitrectomy for endophthalmitis after an intravitreal injection of bevacizumab. Design: Retrospective case report. Methods: An 84-year-old male developed sympathetic ophthalmia 4 months after vitrectomy for endophthalmitis following an intravitreal injection. The inciting blind eye was enucleated. Results: Histopathology demonstrated sympathetic ophthalmia and phacoanaphylactic endophthalmitis. Visual acuity improved from 20/200 to 20/30 in the sympathizing eye with a combination of oral prednisone and azathioprine. Conclusions: Sympathetic ophthalmia can develop following exogenous endophthalmitis but has a good visual prognosis with appropriate treatment.
ISSN:0927-3948
1744-5078
DOI:10.1080/09273940802409951