Proinflammatory cytokines and hemostatic system in patients with chronic obstructive pulmonary disease

The prothrombotic state frequently observed in patients with chronic obstructive pulmonary disease (COPD) may be related to a systemic inflammatory response. In the present study plasma interleukin-6 (IL-6), IL-2 and IL-1 levels have been investigated in 33 patients with COPD. In vitro platelet acti...

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Bibliographic Details
Published in:Platelets (Edinburgh) 1997, Vol.8 (4), p.255-260
Main Author: Ferroni, S. Basili, C. Alessandri, M. Vieri, F. Martini, A. Belogi, F.M. Pulcinelli, C. Cordova, P.P. Gazzaniga, P.
Format: Article
Language:English
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Summary:The prothrombotic state frequently observed in patients with chronic obstructive pulmonary disease (COPD) may be related to a systemic inflammatory response. In the present study plasma interleukin-6 (IL-6), IL-2 and IL-1 levels have been investigated in 33 patients with COPD. In vitro platelet activity, plasma C-reactive protein (CRP) and fibrinogen levels were also determined in all patients. The results obtained demonstrated that plasma IL-6 levels were significantly higher in the patient group compared with a control population ageand sex-matched ( P
ISSN:0953-7104
1369-1635
DOI:10.1080/09537109777294