Aseptic loosening, not only a question of wear: A review of different theories

Today, aseptic loosening is the most common cause of revision of major arthroplasties. Aseptic loosening accounts for more than two-thirds of hip revisions and almost one-half of knee revisions in Sweden. Several theories on the cause of aseptic loosening have been proposed. Most of these theories,...

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Bibliographic Details
Published in:Acta orthopaedica 2006, Vol.77 (2), p.177-197
Main Authors: Sundfeldt, Mikael, V Carlsson, Lars, B Johansson, Carina, Thomsen, Peter, Gretzer, Christina
Format: Article
Language:English
Subjects:
Animals
Arthroplasty
Arthroplasty, Replacement, Hip - adverse effects
Arthroplasty, Replacement, Hip - instrumentation
Arthroplasty, Replacement, Knee - adverse effects
Arthroplasty, Replacement, Knee - instrumentation
Biological and medical sciences
Biomaterials Science
Biomaterialvetenskap
Bone Cements
Bone Density
Bone Resorption - etiology
Ceramics
Diseases of the osteoarticular system
Equipment Failure Analysis
Hip Prosthesis - adverse effects
Hip/adverse effects/instrumentation
Humans
Kirurgi
Knee Prosthesis - adverse effects
Knee/adverse effects/instrumentation
Medical sciences
MEDICIN
MEDICINE
Particle Size
Polyethylenes
Prosthesis Design
Prosthesis Failure
Reoperation
Replacement
Surface Properties
Surgery
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Description
Summary:Today, aseptic loosening is the most common cause of revision of major arthroplasties. Aseptic loosening accounts for more than two-thirds of hip revisions and almost one-half of knee revisions in Sweden. Several theories on the cause of aseptic loosening have been proposed. Most of these theories, however, are based on empiric observations, experimental animal models or anecdotal cases. In this review, we discuss the most common theories concerning aseptic loosening. It emerges from this review that aseptic loosening has a multifactorial etiology and cannot be explained by a single theory.
ISSN:1745-3674
1745-3682
1745-3682
DOI:10.1080/17453670610045902