Intramedullary Subependymoma of the Cervical Spinal Cord: A Case Report with Immunohistochemical Study

ABSTRACT Spinal subependymomas, which have a relatively benign nature, are very rare tumors. It is difficult to distinguish spinal subependymomas from other intramedullary spinal tumors based on neuroradiological findings. A case of cervical intramedullary subependymoma in a 63-year-old female is re...

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Bibliographic Details
Published in:International journal of neuroscience 2010-08, Vol.120 (10), p.676-679
Main Authors: Zenmyo, Michihisa, Ishido, Yasuhiro, Terahara, Mikio, Yamamoto, Takuya, Tanimoto, Akihide, Komiya, Setsuro, Ijiri, Kosei
Format: Article
Language:English
Subjects:
astrocytoma
Ependyma - chemistry
Ependyma - pathology
Ependyma - surgery
ependymoma
Female
Glioma, Subependymal - chemistry
Glioma, Subependymal - pathology
Glioma, Subependymal - surgery
Humans
magnetic resonance imaging
Middle Aged
Spinal Cord - chemistry
Spinal Cord - pathology
Spinal Cord - surgery
Spinal Cord Neoplasms - chemistry
Spinal Cord Neoplasms - pathology
Spinal Cord Neoplasms - surgery
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Summary:ABSTRACT Spinal subependymomas, which have a relatively benign nature, are very rare tumors. It is difficult to distinguish spinal subependymomas from other intramedullary spinal tumors based on neuroradiological findings. A case of cervical intramedullary subependymoma in a 63-year-old female is reported. The diffused enlargement of the spinal cord at C2 level involved the lesion with isointensity on a T1-weighted MRI and relatively high intensity on a T2-weighted MRI. Enhancement in the small part of the tumor was observed on a T1-weighted MRI with gadolinium administration. The tumor occupied the left side of the spinal cord, and was totally removed through a laminoplasty of C2. Immunohistochemistry was useful for pathological diagnosis. The clinical feature of this patient is described with the review of literatures.
ISSN:0020-7454
1563-5279
1543-5245
DOI:10.3109/00207454.2010.509894