Postradiation Squamous Cell Cancer of the Breast

Abstract Primary squamous cell carcinoma of the breast is a rare clinical entity. We diagnosed a patient who presented with a pure squamous cell cancer of the breast 12 years after local radiation for a primary adenocarcinoma of breast. Previously reported cancers related to radiation of the breast...

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Bibliographic Details
Published in:Cancer investigation 2000, Vol.18 (4), p.343-346
Main Authors: Singh, Hardeep, Williams, Susan P., Kinsella, Virginia, Lynch, Garrett R.
Format: Article
Language:English
Subjects:
Adenocarcinoma - pathology
Adenocarcinoma - radiotherapy
Biological and medical sciences
Breast Neoplasms - etiology
Breast Neoplasms - pathology
Breast Neoplasms - radiotherapy
Carcinoma, Squamous Cell - etiology
Carcinoma, Squamous Cell - pathology
Drug toxicity and drugs side effects treatment
Female
Humans
Medical sciences
Middle Aged
Neoplasms, Radiation-Induced - radiotherapy
Pharmacology. Drug treatments
Radiotherapy - adverse effects
Toxicity: urogenital system
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Summary:Abstract Primary squamous cell carcinoma of the breast is a rare clinical entity. We diagnosed a patient who presented with a pure squamous cell cancer of the breast 12 years after local radiation for a primary adenocarcinoma of breast. Previously reported cancers related to radiation of the breast have been squamous cell of skin and esophagus and sarcomas, especially angiosarcomas, and on literature review this is the first reported case of primary squamous carcinoma of the breast related to previous radiation. Although our observation suggests a possible link, no established cause and effect relationship is known at this point.
ISSN:0735-7907
1532-4192
DOI:10.3109/07357900009012177