Diagnostic and Therapeutic Endoscopy in Children and Adolescents with Cancer

Chemotherapy regimes in children with cancer often cause gastrointestinal side effects. Only limited data exist on the use of endoscopy in this group of patients. Methods: Retrospective review over a time period of 8.5 years identified 57 endoscopies (49 upper endoscopies, four colonoscopies, three...

Full description

Saved in:
Bibliographic Details
Published in:Pediatric hematology and oncology 2012-08, Vol.29 (5), p.450-460
Main Authors: Buderus, Stephan, Sonderkötter, Hannah, Fleischhack, Gudrun, Lentze, Michael J.
Format: Article
Language:English
Subjects:
Adolescent
Adult
Biopsy
chemotherapy
Child
Child, Preschool
Digestive System Diseases - pathology
endoscopy
Endoscopy, Digestive System - adverse effects
Endoscopy, Digestive System - methods
Female
gastroenterology
Humans
Infant
infections
Male
Neoplasms - pathology
nutrition
pediatric oncology
Retrospective Studies
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Chemotherapy regimes in children with cancer often cause gastrointestinal side effects. Only limited data exist on the use of endoscopy in this group of patients. Methods: Retrospective review over a time period of 8.5 years identified 57 endoscopies (49 upper endoscopies, four colonoscopies, three sigmoidoscopies, one rectoscopy) in 38 patients (mean age 12.8 years). Seventeen children (45%) had hematological malignancies and 21 (55%) had solid tumors. In 12 children, platelet count was 38.5°C) after colonoscopy, one localized infection after PEG tube placement, and two episodes of temporary desaturation. No association of neutropenia with more infections was observed. No bleeding in thrombocytopenic patients was observed. Conclusion: The data show that endoscopy in high-risk pediatric patients with malignant diseases is a safe procedure. Endoscopy reveals relevant information and have therapeutic impact with high probability. Tube placement techniques can help to maintain EN.
ISSN:0888-0018
1521-0669
DOI:10.3109/08880018.2012.678568