Optic Disc Neovascularization Revealing Neurosyphilis

Purpose: To report a case of neurosyphilis revealed by bilateral optic disc neovascularization. Design: Case report. Methods: A 39-year-old man presented with a 6-month history of progressive visual loss (20/25 RE, 20/1200 LE) and transient headaches. Fundus examination demonstrateda 1+ vitritis, mi...

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Bibliographic Details
Published in:Ocular immunology and inflammation 2012-12, Vol.20 (6), p.464-467
Main Authors: Trechot, F., Maalouf, T., Kaminsky, P., Angioi, K.
Format: Article
Language:English
Subjects:
Adult
Chronic uveitis
Diagnosis, Differential
Fluorescein Angiography
Fundus Oculi
Humans
Male
Neovascularization, Pathologic - diagnosis
Neovascularization, Pathologic - etiology
Neurosyphilis
Neurosyphilis - complications
Neurosyphilis - diagnosis
Optic disc neovascularization
Optic Disk - blood supply
Optic Nerve Diseases - diagnosis
Optic Nerve Diseases - etiology
Treponema pallidum
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Summary:Purpose: To report a case of neurosyphilis revealed by bilateral optic disc neovascularization. Design: Case report. Methods: A 39-year-old man presented with a 6-month history of progressive visual loss (20/25 RE, 20/1200 LE) and transient headaches. Fundus examination demonstrateda 1+ vitritis, mild macular edema and large optic disc neovascularization in both eyes. Serological tests for syphilis were positive. Results: Specific antibiotics and systemic steroids were undertaken and complete regression of disc neovascularization was observed within 6 months. Conclusion: Optic disc neovascularization, which is a rare manifestation of chronic uveitis, may lead to the diagnosis of neurosyphilis and be successfully treated by specific antibiotic and steroid therapy.
ISSN:0927-3948
1744-5078
DOI:10.3109/09273948.2012.714043