Effects of Angiotensin II Receptor Blockers on the Relationships Between Ambulatory Blood Pressure and Anti-Hypertensive Effects, Autonomic Function, and Health-Related Quality of Life

The aim of the present study was to examine the relationships between the anti-hypertensive effects, autonomic function, and health-related quality of life (HRQOL) following treatment of hypertensive subjects with angiotensin receptor blockers (ARBs) in hypertensives. Nineteen patients with hyperten...

Full description

Saved in:
Bibliographic Details
Published in:Clinical and experimental hypertension (1993) 2009-12, Vol.31 (8), p.680-689
Main Authors: Okano, Yasuko, Tamura, Kouichi, Masuda, Shinitirou, Ozawa, Motoko, Tochikubo, Osamu, Umemura, Satoshi
Format: Article
Language:English
Subjects:
Aged
ambulatory blood pressure monitoring
Angiotensin II Type 1 Receptor Blockers - pharmacology
Angiotensin II Type 1 Receptor Blockers - therapeutic use
angiotensin ││ receptor blocker
autonomic function
Benzimidazoles - therapeutic use
Benzoates - therapeutic use
Blood Pressure - drug effects
Blood Pressure Monitoring, Ambulatory
Circadian Rhythm - drug effects
Female
health-related QOL
Heart Rate - drug effects
Humans
Hypertension - drug therapy
Hypertension - physiopathology
Imidazoles - therapeutic use
Losartan - therapeutic use
Male
Middle Aged
Quality of Life
Sympathetic Nervous System - drug effects
Tetrazoles - therapeutic use
Treatment Outcome
Valine - analogs & derivatives
Valine - therapeutic use
Valsartan
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:The aim of the present study was to examine the relationships between the anti-hypertensive effects, autonomic function, and health-related quality of life (HRQOL) following treatment of hypertensive subjects with angiotensin receptor blockers (ARBs) in hypertensives. Nineteen patients with hypertension were assigned randomly to daily treatment with ARBs. After 16 weeks of treatment, blood pressure (BP) and 24 h the ratio of low frequency to high frequency component (LF HF), an index of sympathovagal balance were decreased by ARBs. The HRQOL scores improved during the study. In this study, ARB therapy was associated with an improvement in BP, autonomic function, and HRQOL.
ISSN:1064-1963
1525-6006
DOI:10.3109/10641960903407041