Pathogenesis and Current Management of Gastro-oesophageal-reflux-related Asthma

In the past decade the use of proton pump inhibitors on the one hand an aggressive surgical approach on the other hand have revolutionised the treatment of gastro-oesophageal reflux disease (gord). many studies have suggested that the successful management of gord results in improvement of the sympt...

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Bibliographic Details
Published in:The European journal of surgery 2000, Vol.166 (8), p.596-601
Main Authors: Menes, Tehillah, Lelcuk, Shlomo, Spivak, Hadar
Format: Article
Language:English
Online Access:Get full text
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Summary:In the past decade the use of proton pump inhibitors on the one hand an aggressive surgical approach on the other hand have revolutionised the treatment of gastro-oesophageal reflux disease (gord). many studies have suggested that the successful management of gord results in improvement of the symptoms of asthma which coexist in many of these patients. in this paper we review the pathogenesis and the medical and surgical treatment of gor-related asthma. both anti-reflux operations and anti-acid medications improve gord and gor-related asthma. although anti-reflux surgery is superior to h2 blockers, there are not sufficient data to evaluate proton pump inhibitors compared with operation in controlling the symptoms of asthma.
ISSN:1102-4151
1741-9271
DOI:10.3109/110241500750008222