Twenty years of amyloid arthropathy research in chickens

AA amyloidosis (AAA) is a disease known as amyloid arthropathy in chicken, which represents substantial economic losses, in addition to welfare concerns. Enterococcus faecalis (E. faecalis) is the major pathogen found in field outbreaks of amyloid arthropathy and its specific association with this d...

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Bibliographic Details
Published in:World's Poultry Science Journal 2016-09, Vol.72 (3), p.495-508
Main Authors: BLANCO, A.E., BARZ, M., ICKEN, W., CAVERO, D., MAZAHERI, A., VOSS, M., SCHMUTZ, M., PREISINGER, R.
Format: Article
Language:English
Subjects:
amyloid
amyloid arthropathy
chicken
Enterococcus faecalis
layer
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Summary:AA amyloidosis (AAA) is a disease known as amyloid arthropathy in chicken, which represents substantial economic losses, in addition to welfare concerns. Enterococcus faecalis (E. faecalis) is the major pathogen found in field outbreaks of amyloid arthropathy and its specific association with this disease has been extensively confirmed. The following review discusses the sequence types of E. faecalis associated with AAA that have been identified and characterised both poultry and humans and provide different hypotheses and theories about pathogenesis and transmission of this disease. This article covers the pathology both in field and induced cases of avian amyloidosis and concludes with approaches for a possible treatment, needs for further research and future perspectives. This paper is a consolidation of current knowledge on AAA in chickens which has been obtained over the last twenty years.
ISSN:0043-9339
1743-4777
DOI:10.1017/S0043933916000453