SYNTHESIS, CHARACTERIZATION, AND REPRESENTATIVE CRYSTAL STRUCTURE OF LIPOPHILIC PLATINUMII (HOMOPIPERAZINE)CARBOXYLATE COMPLEXES

• Published in: Journal of coordination chemistry 2001-01, Vol.52 (3), p.273-287
• Main Authors: Ali, Mohammad S., Powers, Christopher A., Whitmire, Kenton H., Guzman-Jimenez, Ilse, Khokhar, Abdul R.
• Format: Article
• Language: eng ; jpn
• Subjects: Carboxylate; Crystal structure; Homopiperazine; Platinum(II); Synthesis
• ISSN: 0095-8972; 1029-0389
• DOI: 10.1080/00958970108022593

A series of new lipophilic platinum(II) complexes of the type [Pt(HPIP)L 2 ] and [Pt(HPIP)L] (where HPIP = homopiperazine; L = acetate, propionate, butyrate, pentanoate, hexanoate, heptanoate, octanoate, nonanoate, decanoate, undecanoate, laureate, tridecanoate, myristate, pentadecanoate, palmitate, or heptadecanoate; and LL = oxalate, or tartronate) were synthesized and characterized by elemental analysis, IR, 13 CNMR, and 195 Pt NMR. In addition, the crystal structure of a representative complex [Pt II (HPIP)(pentadecanoate) 2 ], was determined by X-ray diffraction. The crystals were monoclinic, space group P2 1 /c, with a = 28.212(6)Å, b = 3.661(3)Å, c = 10.218(2)Å, and Z = 4. A total of 3940 reflections were collected, and the structure refined to R1 = 0.0522 and wR2 = 0.1333. The slightly distorted square plane of the platinum included the amino groups of the HPIP molecule in cis positions and oxygens from two monodentate pentadecanoates. The HPIP molecule was in a boat conformation and formed five- and six-member chelating rings with platinum. Together, these molecules formed an intricate network of intermolecular hydrogen bonds that held the crystal lattices together.