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Some Reactions of 4,6-Diaminopyrimidinethione

Reaction of 4,6-diamino-2(1H)-pyrimidinethione (1) with p-toluene-sulfonyl hydrazine, nitrous acid and carbon disulfide afforded the compounds (2, 3) and (4) respectively. Compound (3) easily reacted with anthranilic acid, semicarbazide thiosemicarbazide and acid hydrazides and gave the polynuclearh...

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Bibliographic Details
Published in:Phosphorus, sulfur, and silicon and the related elements sulfur, and silicon and the related elements, 2008-01, Vol.183 (1), p.69-73
Main Author: Ahmed, Gamal A.
Format: Article
Language:English
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Summary:Reaction of 4,6-diamino-2(1H)-pyrimidinethione (1) with p-toluene-sulfonyl hydrazine, nitrous acid and carbon disulfide afforded the compounds (2, 3) and (4) respectively. Compound (3) easily reacted with anthranilic acid, semicarbazide thiosemicarbazide and acid hydrazides and gave the polynuclearheterocyclic compounds (5, 6 a,b ) and (8 a,b ) respectively. Also, compound (4) yielded the tricyclic compound 7 when reacted with ethylchloroformate. The purpose of this article is synthesis of biologically active polynuclear heterocyclic compounds.
ISSN:1042-6507
1563-5325
DOI:10.1080/10426500701556981