Relapsed Plasma Cell Leukaemia Presenting with Aggressive Extramedullary Plasmacytomas in the Meninges and Testis--A Missed Opportunity for Induction CNS Prophylaxis

After initial treatment, a 54-year-old male with plasma cell leukaemia developed extramedullary relapse in the testis and meninges without evidence of bone marrow involvement. We postulate that the central nervous system (CNS) and testis may have served as sanctuary sites for the disease during init...

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Bibliographic Details
Published in:Leukemia & lymphoma 2002, Vol.43 (4), p.893-896
Main Authors: Wellwood, Jeremy, Taylor, Kerry, Wright, Susan, Bentley, Mark, Hill, Geoff, Phan, Huong, Norris, Debra, Livsey, Roger
Format: Article
Language:English
Subjects:
Cns Prophylaxis
Extramedullary Plasmacytoma
Humans
Leukemia, Plasma Cell - pathology
Leukemia, Plasma Cell - therapy
Male
Meningeal Neoplasms - pathology
Meningeal Neoplasms - prevention & control
Meningeal Neoplasms - secondary
Middle Aged
Multiple Myeloma
Plasma Cell Leukaemia
Plasmacytoma - pathology
Plasmacytoma - secondary
Recurrence
Testicular Neoplasms - pathology
Testicular Neoplasms - secondary
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Summary:After initial treatment, a 54-year-old male with plasma cell leukaemia developed extramedullary relapse in the testis and meninges without evidence of bone marrow involvement. We postulate that the central nervous system (CNS) and testis may have served as sanctuary sites for the disease during initial treatment. A role for CNS prophylaxis in plasma cell leukaemia is suggested.
ISSN:1042-8194
1029-2403
DOI:10.1080/10428190290017060