Assessment of Potential Human Health Risks from Arsenic in CCA-Treated Wood

• Published in: Human and ecological risk assessment 2004-12, Vol.10 (6), p.1019-1067
• Main Authors: Dubé, E. M., Boyce, C. Petito, Beck, B. D., Lewandowski, T., Schettler, S.
• Format: Article
• Language: English
• Subjects: Arsenic; Cancer; CCA; dislodgeable residue; Health risk assessment; Human exposure; human health risk assessment; Preservatives; Risk factors; soil arsenic; Soils; treated wood
• ISSN: 1080-7039; 1549-7860
• DOI: 10.1080/10807030490887131

Chromated copper arsenate (CCA) is a chemical preservative used to treat wood for a variety of outdoor uses, including decks, fencing, and play structures. This article describes a methodology to quantify exposures to arsenic from CCA-treated wood. Exposure was evaluated for ingestion and dermal contact with arsenic-containing residue on treated wood surfaces (dislodgeable arsenic), and ingestion, dermal contact, and inhalation of soil containing arsenic originating from treated wood structures. Standard approaches were used to quantify exposures to arsenic in soil. In the absence of standard approaches for exposures to dislodgeable residue, an empirical approach was developed, extrapolating from studies of soil loadings on hands and soil ingestion rates to estimate the amount of dislodgeable residue on hands that is subsequently ingested. Results from animal studies were used to develop relative bioavailability estimates for dislodgeable and soil arsenic. A focused sensitivity analysis demonstrated that the assumptions used regarding hand loading and subsequent incidental ingestion of dislodgeable arsenic had the most significant impact on the results. This assessment indicates low uptake of arsenic into the body, resulting in incremental lifetime cancer risks within USEPA's target risk levels. We compare this approach to other methodologies used to assess exposures to treated wood.