Myoclonic jerks due to acute bromovalerylurea intoxication

Background. Bromides are still sold as sedatives, antitussives, and anticonvulsants in many countries. Bromovalerylurea is a bromide-containing sedative-hypnotic that is occasionally combined with non-steroidal anti-inflammatory drugs in over-the-counter products. Chronic intake of excessive bromova...

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Bibliographic Details
Published in:Clinical Toxicology 2008, Vol.46 (9), p.861-863
Main Authors: Lin, Jiun-Nong, Lin, Hsing-Lin, Huang, Chun-Kai, Lai, Chung-Hsu, Chung, Hsing-Chun, Liang, Shiou-Haur, Lin, Hsi-Hsun
Format: Report
Language:English
Subjects:
Bromide
Bromovalerylurea
Myoclonic jerks
Myoclonus
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Summary:Background. Bromides are still sold as sedatives, antitussives, and anticonvulsants in many countries. Bromovalerylurea is a bromide-containing sedative-hypnotic that is occasionally combined with non-steroidal anti-inflammatory drugs in over-the-counter products. Chronic intake of excessive bromovalerylurea can produce bromide intoxication, but acute bromovalerylurea intoxication presenting with myoclonic jerks has never been described. Case report. A 23-year-old woman was brought to our emergency department with unusual drowsiness. Her physical examination was normal except for frequent myoclonic jerks in all extremities that could be triggered by moving the patient or by noxious stimuli. Initial blood tests results were normal; the serum bromide concentration was 81.0 mg/L (reference
ISSN:1556-3650
1556-9519
DOI:10.1080/15563650802020361