Powder Sampling

ABSTRACT The factors involved when sampling powder mixes have been reviewed. The various methods are evaluated (manual, automatic, and sub-sampling) and the errors incurred are discussed. Certain rules have been applied to various samplers and their suitability for powder mixtures are described. The...

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Bibliographic Details
Published in:Drug development and industrial pharmacy 2002, Vol.28 (2), p.107-117
Main Authors: Venables, Helena J., Wells, J. I.
Format: Article
Language:English
Subjects:
Automatic sampling
Automation
Bias
Biological and medical sciences
Drug Industry
Error
General pharmacology
Manual sampling
Medical sciences
Pharmaceutical technology. Pharmaceutical industry
Pharmacology. Drug treatments
Powder mixing
Powders
Quality Control
Sampling
Specimen Handling - methods
Sub-sampling
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Summary:ABSTRACT The factors involved when sampling powder mixes have been reviewed. The various methods are evaluated (manual, automatic, and sub-sampling) and the errors incurred are discussed. Certain rules have been applied to various samplers and their suitability for powder mixtures are described. The spinning riffler is apparently the most suitable, while the use of sample thieves should be avoided due to error and bias.
ISSN:0363-9045
1520-5762
DOI:10.1081/DDC-120002443