MooPoong (Gye Young Jeong) Increases HDL-Cholesterol but Decreases LDL Cholesterol and Body-Weight

MooPoong (MP, Gye Young Jeong), a Korean traditional wine, has been used as a prevention and treatment agent of blood circulatory trouble. To evaluate such an effect of MP, we analyzed whether the plasma levels of low-density lipoprotein (LDL) cholesterol, high-density lipoprotein (HDL) cholesterol,...

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Bibliographic Details
Published in:Immunopharmacology and immunotoxicology 2004-01, Vol.26 (2), p.225-232
Main Authors: Chung, Hwan-Suck, Hong, Seung-Heon, Do, Keum-Rok, Rhee, Hyung-Koo, Jung, Sung-Ki, Hwang, Woo-Jun, Kim, Hyung-Min
Format: Article
Language:English
Subjects:
Alanine Transaminase - blood
Animals
Aspartate Aminotransferases - blood
Blood circulatory trouble
Body Weight
Cholesterol, HDL - blood
Cholesterol, LDL - blood
Dietary Fats - administration & dosage
High-density lipoprotein-cholesterol
High-fat diet
Korea
Low-density lipoprotein-cholesterol
Male
MooPoong
Overweight
Rats
Rats, Sprague-Dawley
Weight Gain
Wine
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Summary:MooPoong (MP, Gye Young Jeong), a Korean traditional wine, has been used as a prevention and treatment agent of blood circulatory trouble. To evaluate such an effect of MP, we analyzed whether the plasma levels of low-density lipoprotein (LDL) cholesterol, high-density lipoprotein (HDL) cholesterol, and body weight change after rats were fed on high fat diet with MP for 8 weeks. Plasma LDL cholesterol level decreased by 5.6% in 0.128% MP treated group and by 11.1% in 0.640% MP treated group. However, HDL cholesterol was increased by 6.7% in 0.128% MP diet group and 33.3% in 0.640% MP diet group. In addition, there was a significant weight loss in the MP treated group compared with the high-fat diet group (P < 0.05). Our findings indicate that MP may contain compounds with actions which can treat blood circulatory trouble as well as overweight.
ISSN:0892-3973
1532-2513
DOI:10.1081/IPH-120037718