SYNTHESIS OF A NEW CHIRAL AMINE:(S)-5,5-DIMETHYL-2-METHOXYMETHYL-PYRROLIDINE

The title compound, a potential 'quat' auxiliary,was prepared from (S)-glutamic acid derivatives like (S)-N-Benzyl-5-methoxymethyl-2-pyrrolidinone 1. Other routes starting from (S)-pyroglutamic acid in an attempt to bypass N-Aryl compounds like 1 were also tested, but have not rendered the...

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Bibliographic Details
Published in:Synthetic communications 2001-01, Vol.31 (5), p.697-706
Main Authors: Breña-Valle, Leonardo J., Cruz-Almanza, Raymundo, Guadarrama-Morales, F. Oscar
Format: Article
Language:English
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Summary:The title compound, a potential 'quat' auxiliary,was prepared from (S)-glutamic acid derivatives like (S)-N-Benzyl-5-methoxymethyl-2-pyrrolidinone 1. Other routes starting from (S)-pyroglutamic acid in an attempt to bypass N-Aryl compounds like 1 were also tested, but have not rendered the expected results yet.
ISSN:0039-7911
1532-2432
DOI:10.1081/SCC-100103258