Microwave-Assisted Efficient Synthesis of Dihydropyrimidines in Solvent-Free Condition

An efficient synthesis of 3,4-dihydropyrimidinones from an aldehyde, a ketoester, and a urea or thiourea using a catalytic amount of ferric chloride hexahydrate is described. Microwave irradiation has been used to accelerate the synthesis of the Biginelli compounds under solvent-free conditions and...

Full description

Saved in:
Bibliographic Details
Published in:Synthetic communications 2004, Vol.34 (18), p.3335-3341
Main Authors: Mirza-Aghayan, Maryam, Bolourtchian, Mohammad, Hosseini, Maryam
Format: Article
Language:English
Subjects:
Biginelli compounds
Ferric chloride hexahydrate
Microwave irradiation
Solvent-free condition
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:An efficient synthesis of 3,4-dihydropyrimidinones from an aldehyde, a ketoester, and a urea or thiourea using a catalytic amount of ferric chloride hexahydrate is described. Microwave irradiation has been used to accelerate the synthesis of the Biginelli compounds under solvent-free conditions and in a short reaction time and with good yield.
ISSN:0039-7911
1532-2432
DOI:10.1081/SCC-200030577