Age-Related Differences of Blood Pressure Profile in Essential Hypertension

The purpose was to assess age-related circadian changes of blood pressure profile (BPP) employing a truncated Fourier series with four harmonics (tFs) in patients with essential hypertension. The study was performed on 32 patients with essential hypertension divided in two groups: (A) 15 patients yo...

Full description

Saved in:
Bibliographic Details
Published in:Chronobiology international 1997-01, Vol.14 (4), p.397-407
Main Authors: Scorzoni, Daniela, Bazzanini, Francesco, Brunazzi, Maria Cristiana, Md, Fabio Chirilto, Biondi, Pietro, Hölzl, Anna, Musacci, GianFranca, Longhini, Carlo
Format: Article
Language:English
Subjects:
Adult
Age
Aged
Aged, 80 and over
Aging - physiology
Arterial hypertension. Arterial hypotension
Biological and medical sciences
Blood and lymphatic vessels
Blood Pressure - physiology
Blood pressure profile
Cardiology. Vascular system
Cardiovascular Diseases - etiology
Circadian rhythm
Circadian Rhythm - physiology
Clinical manifestations. Epidemiology. Investigative techniques. Etiology
Essential hypertension
Fourier Analysis
Fourier series
Humans
Hypertension - complications
Hypertension - physiopathology
Medical sciences
Middle Aged
Models, Cardiovascular
Risk Factors
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:The purpose was to assess age-related circadian changes of blood pressure profile (BPP) employing a truncated Fourier series with four harmonics (tFs) in patients with essential hypertension. The study was performed on 32 patients with essential hypertension divided in two groups: (A) 15 patients younger than 55 years and (B) 17 patients older than 60 years. Systolic blood pressure (SBP) and diastolic blood pressure (DBP) were monitored every 20 minutes for 24h with a noninvasive portable device (SpaceLabs 90202). To evaluate the existence of SBP and DBP circadian rhythms a one-sample runs-test was performed and the mesor, amplitude, and acrophase from the overall curve of each patient were obtained by tFs. In both groups, SBP and DBP profiles showed a first peak in the late morning and a second peak in the early evening around the same hours. The two peaks in the SBP profile were higher and the two peaks in the DBP profile were lower in older patients than in younger ones (p. 01, p . 3, p>. 05). The truncated Fourier series with four harmonics evidences different age-related BP profiles characterized by two peaks with higher SBP and lower DBP in elderly patients. These changes of BPP are in accordance with the reported higher risk of cardiovascular events observed around the same hours. (Chronobiology International, 14(4), 397-407, 1997)
ISSN:0742-0528
1525-6073
DOI:10.3109/07420529709001460