Hemophagocytic Syndrome Associated with Inappropiate Secretion of Antidiuretic Hormone in Lymphoma and Acute Myeloblastic Leukemia: Report of Two Cases

Hemophagocytic syndrome (HPS) is a rare clinicopathological disorder characterized by systemic proliferation of phagocytizing histiocytes associated with fever, cytopenias, lymphadenopathy, hepatosplenomegaly, and disseminated intravascular coagulopathy. We present the association of hemophagocytic...

Full description

Saved in:
Bibliographic Details
Published in:Leukemia & Lymphoma 2001, Vol.42 (6), p.1401-1404
Main Authors: Demirkan, Fatih, Vural, Filiz, Özsan, G. Hayri, Özcan, M. Ali, Özkal, SermiN, Ündar, Bülent
Format: Report
Language:English
Subjects:
acute myeloblastic leukemia (AML)
anaplastic large cell lymphoma (ALCL)
hemophagocytic syndrome (HPS)
inappropriate secretion of antidiuretic hormone (SIADH)
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
cited_by
cites
container_end_page 1404
container_issue 6
container_start_page 1401
container_title Leukemia & Lymphoma
container_volume 42
creator Demirkan, Fatih
Vural, Filiz
Özsan, G. Hayri
Özcan, M. Ali
Özkal, SermiN
Ündar, Bülent
description Hemophagocytic syndrome (HPS) is a rare clinicopathological disorder characterized by systemic proliferation of phagocytizing histiocytes associated with fever, cytopenias, lymphadenopathy, hepatosplenomegaly, and disseminated intravascular coagulopathy. We present the association of hemophagocytic syndrome associated with inappropriate secretion of antidiuretic hormone (SIADH) in two cases of hematological malignancies; anaplastic large cell lymphoma (ALCL) and acute myeloblastic leukemia (AML M4) In the patient with lymphoma, the diagnosis of lymphoma, HPS and SIADH were concurrent. In the patient with AML, HPS and SIADH were observed while the patient was in hematological remission. Thus it seems that patients with HPS may also carry a risk for the development of SIADH; the relationship with HPS and SIADH should be further investigated.
doi_str_mv 10.3109/10428190109097769
format report
fullrecord <record><control><sourceid>informaworld</sourceid><recordid>TN_cdi_informaworld_taylorfrancis_310_3109_10428190109097769</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>11273967</sourcerecordid><originalsourceid>FETCH-informaworld_taylorfrancis_310_3109_104281901090977693</originalsourceid><addsrcrecordid>eNqlUE1LxDAUDKLg-vEDvL0_UE0_3DXipSxKhfXi7r0809RG27yQpJT-Ev-uDXjbo4fhDcPMPBjGblJ-m6dc3KW8yB5SwRfOxWazFidslfJMJFnB89PIiyxZDMU5u_D-i3N-L9bZiv1UaiDb4SfJOWgJ-9k0jgYFpfckNQbVwKRDB68GrXVkowR7JZ0KmgxQC6UJutFjFCRU5AYyCrSB3TzYjgYENA2Uclxyb7Pq6aNHH607NX6rQeMjvCtLLsSuw0SwRa_8FTtrsffq-u9esqeX58O2SrRplxc4keubOuDck2sdGql9vQwRIeqjMfJ_xn8Bn-Bukg</addsrcrecordid><sourcetype>Publisher</sourcetype><iscdi>true</iscdi><recordtype>report</recordtype></control><display><type>report</type><title>Hemophagocytic Syndrome Associated with Inappropiate Secretion of Antidiuretic Hormone in Lymphoma and Acute Myeloblastic Leukemia: Report of Two Cases</title><source>Taylor and Francis:Jisc Collections:Taylor and Francis Read and Publish Agreement 2024-2025:Medical Collection (Reading list)</source><creator>Demirkan, Fatih ; Vural, Filiz ; Özsan, G. Hayri ; Özcan, M. Ali ; Özkal, SermiN ; Ündar, Bülent</creator><creatorcontrib>Demirkan, Fatih ; Vural, Filiz ; Özsan, G. Hayri ; Özcan, M. Ali ; Özkal, SermiN ; Ündar, Bülent</creatorcontrib><description>Hemophagocytic syndrome (HPS) is a rare clinicopathological disorder characterized by systemic proliferation of phagocytizing histiocytes associated with fever, cytopenias, lymphadenopathy, hepatosplenomegaly, and disseminated intravascular coagulopathy. We present the association of hemophagocytic syndrome associated with inappropriate secretion of antidiuretic hormone (SIADH) in two cases of hematological malignancies; anaplastic large cell lymphoma (ALCL) and acute myeloblastic leukemia (AML M4) In the patient with lymphoma, the diagnosis of lymphoma, HPS and SIADH were concurrent. In the patient with AML, HPS and SIADH were observed while the patient was in hematological remission. Thus it seems that patients with HPS may also carry a risk for the development of SIADH; the relationship with HPS and SIADH should be further investigated.</description><identifier>ISSN: 1042-8194</identifier><identifier>EISSN: 1029-2403</identifier><identifier>DOI: 10.3109/10428190109097769</identifier><language>eng</language><publisher>Taylor &amp; Francis</publisher><subject>acute myeloblastic leukemia (AML) ; anaplastic large cell lymphoma (ALCL) ; hemophagocytic syndrome (HPS) ; inappropriate secretion of antidiuretic hormone (SIADH)</subject><ispartof>Leukemia &amp; Lymphoma, 2001, Vol.42 (6), p.1401-1404</ispartof><rights>2001 Informa UK Ltd All rights reserved: reproduction in whole or part not permitted 2001</rights><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>776,780,4475,27904</link.rule.ids></links><search><creatorcontrib>Demirkan, Fatih</creatorcontrib><creatorcontrib>Vural, Filiz</creatorcontrib><creatorcontrib>Özsan, G. Hayri</creatorcontrib><creatorcontrib>Özcan, M. Ali</creatorcontrib><creatorcontrib>Özkal, SermiN</creatorcontrib><creatorcontrib>Ündar, Bülent</creatorcontrib><title>Hemophagocytic Syndrome Associated with Inappropiate Secretion of Antidiuretic Hormone in Lymphoma and Acute Myeloblastic Leukemia: Report of Two Cases</title><title>Leukemia &amp; Lymphoma</title><description>Hemophagocytic syndrome (HPS) is a rare clinicopathological disorder characterized by systemic proliferation of phagocytizing histiocytes associated with fever, cytopenias, lymphadenopathy, hepatosplenomegaly, and disseminated intravascular coagulopathy. We present the association of hemophagocytic syndrome associated with inappropriate secretion of antidiuretic hormone (SIADH) in two cases of hematological malignancies; anaplastic large cell lymphoma (ALCL) and acute myeloblastic leukemia (AML M4) In the patient with lymphoma, the diagnosis of lymphoma, HPS and SIADH were concurrent. In the patient with AML, HPS and SIADH were observed while the patient was in hematological remission. Thus it seems that patients with HPS may also carry a risk for the development of SIADH; the relationship with HPS and SIADH should be further investigated.</description><subject>acute myeloblastic leukemia (AML)</subject><subject>anaplastic large cell lymphoma (ALCL)</subject><subject>hemophagocytic syndrome (HPS)</subject><subject>inappropriate secretion of antidiuretic hormone (SIADH)</subject><issn>1042-8194</issn><issn>1029-2403</issn><fulltext>true</fulltext><rsrctype>report</rsrctype><creationdate>2001</creationdate><recordtype>report</recordtype><sourceid/><recordid>eNqlUE1LxDAUDKLg-vEDvL0_UE0_3DXipSxKhfXi7r0809RG27yQpJT-Ev-uDXjbo4fhDcPMPBjGblJ-m6dc3KW8yB5SwRfOxWazFidslfJMJFnB89PIiyxZDMU5u_D-i3N-L9bZiv1UaiDb4SfJOWgJ-9k0jgYFpfckNQbVwKRDB68GrXVkowR7JZ0KmgxQC6UJutFjFCRU5AYyCrSB3TzYjgYENA2Uclxyb7Pq6aNHH607NX6rQeMjvCtLLsSuw0SwRa_8FTtrsffq-u9esqeX58O2SrRplxc4keubOuDck2sdGql9vQwRIeqjMfJ_xn8Bn-Bukg</recordid><startdate>20010101</startdate><enddate>20010101</enddate><creator>Demirkan, Fatih</creator><creator>Vural, Filiz</creator><creator>Özsan, G. Hayri</creator><creator>Özcan, M. Ali</creator><creator>Özkal, SermiN</creator><creator>Ündar, Bülent</creator><general>Taylor &amp; Francis</general><scope/></search><sort><creationdate>20010101</creationdate><title>Hemophagocytic Syndrome Associated with Inappropiate Secretion of Antidiuretic Hormone in Lymphoma and Acute Myeloblastic Leukemia: Report of Two Cases</title><author>Demirkan, Fatih ; Vural, Filiz ; Özsan, G. Hayri ; Özcan, M. Ali ; Özkal, SermiN ; Ündar, Bülent</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-informaworld_taylorfrancis_310_3109_104281901090977693</frbrgroupid><rsrctype>reports</rsrctype><prefilter>reports</prefilter><language>eng</language><creationdate>2001</creationdate><topic>acute myeloblastic leukemia (AML)</topic><topic>anaplastic large cell lymphoma (ALCL)</topic><topic>hemophagocytic syndrome (HPS)</topic><topic>inappropriate secretion of antidiuretic hormone (SIADH)</topic><toplevel>online_resources</toplevel><creatorcontrib>Demirkan, Fatih</creatorcontrib><creatorcontrib>Vural, Filiz</creatorcontrib><creatorcontrib>Özsan, G. Hayri</creatorcontrib><creatorcontrib>Özcan, M. Ali</creatorcontrib><creatorcontrib>Özkal, SermiN</creatorcontrib><creatorcontrib>Ündar, Bülent</creatorcontrib></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Demirkan, Fatih</au><au>Vural, Filiz</au><au>Özsan, G. Hayri</au><au>Özcan, M. Ali</au><au>Özkal, SermiN</au><au>Ündar, Bülent</au><format>book</format><genre>unknown</genre><ristype>RPRT</ristype><atitle>Hemophagocytic Syndrome Associated with Inappropiate Secretion of Antidiuretic Hormone in Lymphoma and Acute Myeloblastic Leukemia: Report of Two Cases</atitle><jtitle>Leukemia &amp; Lymphoma</jtitle><date>2001-01-01</date><risdate>2001</risdate><volume>42</volume><issue>6</issue><spage>1401</spage><epage>1404</epage><pages>1401-1404</pages><issn>1042-8194</issn><eissn>1029-2403</eissn><abstract>Hemophagocytic syndrome (HPS) is a rare clinicopathological disorder characterized by systemic proliferation of phagocytizing histiocytes associated with fever, cytopenias, lymphadenopathy, hepatosplenomegaly, and disseminated intravascular coagulopathy. We present the association of hemophagocytic syndrome associated with inappropriate secretion of antidiuretic hormone (SIADH) in two cases of hematological malignancies; anaplastic large cell lymphoma (ALCL) and acute myeloblastic leukemia (AML M4) In the patient with lymphoma, the diagnosis of lymphoma, HPS and SIADH were concurrent. In the patient with AML, HPS and SIADH were observed while the patient was in hematological remission. Thus it seems that patients with HPS may also carry a risk for the development of SIADH; the relationship with HPS and SIADH should be further investigated.</abstract><pub>Taylor &amp; Francis</pub><doi>10.3109/10428190109097769</doi></addata></record>
fulltext fulltext
identifier ISSN: 1042-8194
ispartof Leukemia & Lymphoma, 2001, Vol.42 (6), p.1401-1404
issn 1042-8194
1029-2403
language eng
recordid cdi_informaworld_taylorfrancis_310_3109_10428190109097769
source Taylor and Francis:Jisc Collections:Taylor and Francis Read and Publish Agreement 2024-2025:Medical Collection (Reading list)
subjects acute myeloblastic leukemia (AML)
anaplastic large cell lymphoma (ALCL)
hemophagocytic syndrome (HPS)
inappropriate secretion of antidiuretic hormone (SIADH)
title Hemophagocytic Syndrome Associated with Inappropiate Secretion of Antidiuretic Hormone in Lymphoma and Acute Myeloblastic Leukemia: Report of Two Cases
url http://sfxeu10.hosted.exlibrisgroup.com/loughborough?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-25T01%3A36%3A31IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-informaworld&rft_val_fmt=info:ofi/fmt:kev:mtx:book&rft.genre=unknown&rft.atitle=Hemophagocytic%20Syndrome%20Associated%20with%20Inappropiate%20Secretion%20of%20Antidiuretic%20Hormone%20in%20Lymphoma%20and%20Acute%20Myeloblastic%20Leukemia:%20Report%20of%20Two%20Cases&rft.jtitle=Leukemia%20&%20Lymphoma&rft.au=Demirkan,%20Fatih&rft.date=2001-01-01&rft.volume=42&rft.issue=6&rft.spage=1401&rft.epage=1404&rft.pages=1401-1404&rft.issn=1042-8194&rft.eissn=1029-2403&rft_id=info:doi/10.3109/10428190109097769&rft_dat=%3Cinformaworld%3E11273967%3C/informaworld%3E%3Cgrp_id%3Ecdi_FETCH-informaworld_taylorfrancis_310_3109_104281901090977693%3C/grp_id%3E%3Coa%3E%3C/oa%3E%3Curl%3E%3C/url%3E&rft_id=info:oai/&rft_id=info:pmid/&rfr_iscdi=true