Treatment of Severe Thallium Intoxication

Abstract Case Report: We report a successfully treated case of severe thallium intoxication. In spite of very high serum thallium (5,240 μg/L), symptomatology was minor and recovery complete. Russian Blue was administered, diuresis was enhanced by intravenous fluids and a prolonged hemodialysis was...

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Published in:Clinical toxicology (Philadelphia, Pa.) Pa.), 1997, Vol.35 (1), p.97-100
Main Authors: Malbrain, Manu L.N.G., Lambrecht, Guy L.Y., Zandijk, Erik, Demedts, Paul A., Neels, Hugo M., Lambert, Willy, De Leenheer, André P., Lins, Robert L., Daelemans, Ronny
Format: Article
Language:English
Subjects:
Adult
Antidotes - therapeutic use
Biological and medical sciences
Female
Ferrocyanides - therapeutic use
Gastric Lavage
Humans
Medical sciences
Pesticides, fertilizers and other agrochemicals toxicology
Poisoning - therapy
Potassium Chloride - administration & dosage
Renal Dialysis
Suicide, Attempted
Thallium - blood
Thallium - poisoning
Thallium - urine
Toxicology
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Summary:Abstract Case Report: We report a successfully treated case of severe thallium intoxication. In spite of very high serum thallium (5,240 μg/L), symptomatology was minor and recovery complete. Russian Blue was administered, diuresis was enhanced by intravenous fluids and a prolonged hemodialysis was started early. High blood flows (300 mL/min) and intravenous potassium chloride supplements, to mobilize thallium from the tissues, resulted in good clearances (96 to 150 mL/min). In order to prevent the well known complications, we recommend aggressive treatment of severe thallium intoxication
ISSN:1556-3650
0731-3810
1556-9519
1097-9875
DOI:10.3109/15563659709001173