Possible Serotonin Syndrome from Paroxetine and Clonazepam

The serotonin syndrome is a well-described drug-induced disorder characterized by alterations in mental status, neuromuscular activity, and autonomic nervous system function. It is solely produced by drugs that increase serotonin neurotransmission. We report a possible case of serotonin syndrome pre...

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Bibliographic Details
Published in:Clinical toxicology (Philadelphia, Pa.) Pa.), 1998, Vol.36 (3), p.257-258
Main Authors: Rella, Joseph G., Hoffman, Robert S.
Format: Article
Language:English
Subjects:
Adult
Clonazepam - adverse effects
Contraindications
Drug Interactions
Female
GABA Modulators - adverse effects
Humans
Nervous System Diseases - chemically induced
Paroxetine - adverse effects
Serotonin - metabolism
Serotonin Uptake Inhibitors - adverse effects
Syndrome
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Summary:The serotonin syndrome is a well-described drug-induced disorder characterized by alterations in mental status, neuromuscular activity, and autonomic nervous system function. It is solely produced by drugs that increase serotonin neurotransmission. We report a possible case of serotonin syndrome precipitated by a drug that has previously not been associated with the serotonin syndrome.
ISSN:1556-3650
0731-3810
1556-9519
DOI:10.3109/15563659809028950