Short-duration peripherally inserted central catheters do not alter viscoelastic parameters in healthy dogs

Objective To determine if short-duration peripherally inserted central catheters (PICCs) cause a hypercoagulable state in healthy dogs, based on point-of-care viscoelastic coagulation monitor (VCM). Animals Ten beagle dogs were randomly and equally allocated into control and PICC groups. Procedure C...

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Bibliographic Details
Published in:Canadian veterinary journal 2024-07, Vol.65 (7), p.692-697
Main Authors: Morris, Leah, Galezowski, Angelica, Atilla, Aylin, Menard, Julie
Format: Article
Language:English
Subjects:
Animals
Blood Coagulation - drug effects
Catheterization, Central Venous - veterinary
Catheterization, Peripheral - veterinary
Dogs
Female
Male
Scientific
Time Factors
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Summary:Objective To determine if short-duration peripherally inserted central catheters (PICCs) cause a hypercoagulable state in healthy dogs, based on point-of-care viscoelastic coagulation monitor (VCM). Animals Ten beagle dogs were randomly and equally allocated into control and PICC groups. Procedure Control dogs had VCM analysis on whole blood following direct venipuncture before sedation (T0) and 2 h after sedation (T2). In the experimental group, a PICC was placed (medial saphenous or femoral vein) under sedation and removed after 4 h, with measurements before placement (T0) and 2 and 6 h after placement (T2 and T6, respectively). Parametric data were analyzed using 1-way ANOVA with Holm-Šídák test for multiple comparisons and paired or unpaired Student's t-test. Nonparametric data were analyzed using Friedman test with Dunn multiple comparison test for Wilcoxon matched-pairs signed-rank test, and Mann-Whitney U test for PICC group, control group, and to compare PICC versus control groups, respectively. Results Clot formation time was longer at T2 versus T6 (P = 0.0342, but not clinically relevant) in the PICC group, with no significant differences between the PICC and control groups. Conclusion and clinical relevance Short-term placement of a PICC line did not alter viscoelastic endpoints in healthy beagles.
ISSN:0008-5286