Loading…

Evaluation of temperature changes in a cell culture plate well with absorbing walls containing a 3D model of tumour spheroid under irradiation in the optical range

The temperature conditions for photodynamic therapy of the culture of tumour cells organised in 3D spheroids are studied. The spheroids are placed in the cell culture medium in the well of a special cell culture plate with absorbing walls. A mathematical model is presented that describes the tempera...

Full description

Saved in:
Bibliographic Details
Published in:Quantum electronics (Woodbury, N.Y.) N.Y.), 2020-11, Vol.50 (11), p.1050-1054
Main Authors: Sapogova, N.V., Yuzhakova, D.V., Smirnov, A.A., Shirmanova, M.V., Lukina, M.M., Gavrina, A.I., Izosimova, A.V., Zagaynova, E.V., Kamensky, V.A.
Format: Article
Language:English
Subjects:
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:The temperature conditions for photodynamic therapy of the culture of tumour cells organised in 3D spheroids are studied. The spheroids are placed in the cell culture medium in the well of a special cell culture plate with absorbing walls. A mathematical model is presented that describes the temperature distribution in a well with a cell culture plate heated by optical radiation. It is shown that the temperature in the well volume is not uniformly distributed, and the temperature on the well surface can differ significantly from the temperature in its volume.
ISSN:1063-7818
1468-4799
DOI:10.1070/QEL17338