Simulation of dosimetric consequences of 4D-CT-based motion margin estimation for proton radiotherapy using patient tumor motion data

For the radiation treatment of lung cancer patients, four-dimensional computed tomography (4D-CT) is a common practice used clinically to image tumor motion and subsequently determine the internal target volume (ITV) from the maximum intensity projection (MIP) images. ITV, which is derived from shor...

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Bibliographic Details
Published in:Physics in medicine & biology 2014-02, Vol.59 (4), p.853-867
Main Authors: Koybasi, Ozhan, Mishra, Pankaj, St. James, Sara, Lewis, John H., Seco, Joao
Format: Article
Language:English
Subjects:
Four-Dimensional Computed Tomography
Humans
internal target volume
Lung Neoplasms - diagnostic imaging
Lung Neoplasms - physiopathology
Lung Neoplasms - radiotherapy
lung tumor motion
Models, Biological
Movement
proton radiotherapy
Proton Therapy
Radiometry
Radiotherapy Dosage
Radiotherapy Planning, Computer-Assisted
Respiration
Time Factors
XCAT phantom
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Description
Summary:For the radiation treatment of lung cancer patients, four-dimensional computed tomography (4D-CT) is a common practice used clinically to image tumor motion and subsequently determine the internal target volume (ITV) from the maximum intensity projection (MIP) images. ITV, which is derived from short pre-treatment 4D-CT scan (
ISSN:0031-9155
1361-6560
DOI:10.1088/0031-9155/59/4/853