Ions concentration in blood samples of SJL/J dystrophic mice strains using X-ray fluorescence spectrometry

Star This study proposes an investigation of ions in whole blood of the dystrophic animal model SJL/J (mice strain with dysferlin protein deficiency) and in the control group (C57BL/6J) using the Energy Dispersive X-ray Fluorescence (EDXRF) spectrometry technique. The comparison between control and...

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Bibliographic Details
Published in:Journal of physics. Conference series 2019-07, Vol.1291 (1), p.12023
Main Authors: Giovanni, D N S, Almeida, M R, Zamboni, C B, Metairon, S, Balduino, K N, Suzuki, M F, Bueno, C R
Format: Article
Language:English
Subjects:
Blood
Energy dispersive X ray spectroscopy
Muscular dystrophy
Physics
Scientific imaging
Spectrometry
X-ray fluorescence
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Summary:Star This study proposes an investigation of ions in whole blood of the dystrophic animal model SJL/J (mice strain with dysferlin protein deficiency) and in the control group (C57BL/6J) using the Energy Dispersive X-ray Fluorescence (EDXRF) spectrometry technique. The comparison between control and dystrophic mice results shown an increase in blood for P, S, K and Fe (p < 0.05) while a decrease in Ca (p < 0.05). This elemental analysis will contribute to evaluate the best diagnostic, care and treatment procedures, for the Progressive Muscular Dystrophy.
ISSN:1742-6588
1742-6596
DOI:10.1088/1742-6596/1291/1/012023