Antioxidant and Antimicrobial Activity of Endophytyc Fungi Isolated from Syzygium aqueum Leaves

Syzygium aqueum is a widely used medicinal plant species with ethnomedicinal values. Despite the plant, the endophytes are recognized as a rich source of secondary metabolites with potentially useful pharmacological properties. This study was aimed to identify the endophytic fungi from S.aqueum leav...

Full description

Saved in:
Bibliographic Details
Published in:Journal of physics. Conference series 2021-01, Vol.1751 (1), p.12059
Main Authors: Habisukan, U H, Elfita, Widjajanti, H, Setiawan, A, Kurniawati, A R
Format: Article
Language:English
Subjects:
Antiinfectives and antibacterials
antimicrobial
Antimicrobial agents
antioxidant
Antioxidants
Biological activity
Coliforms
E coli
endophytic fungi
Ethyl acetate
Fungi
Herbal medicine
Metabolites
Physics
Salmonella
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Syzygium aqueum is a widely used medicinal plant species with ethnomedicinal values. Despite the plant, the endophytes are recognized as a rich source of secondary metabolites with potentially useful pharmacological properties. This study was aimed to identify the endophytic fungi from S.aqueum leaves and discover their antioxidant and antimicrobial activity. The ethyl acetate extracts of the isolated endophytic fungi were investigated for their antioxidant and antimicrobial activity using 1,1diphenyl-2-picryl hydrazyl (DPPH) method and paper disc diffusion assay, respectively. The antimicrobial activity was evaluated against three pathogen bacteria : Staphylococcus aureus, Salmonella thypi, and Escherichia coli, and one yeast: Candida albicans. Three endophytic fungi were obtained from S. aqueum leaves. Based on morphological characteristics, those fungi identified as Cochliobolus sp (D22), Penicillium sp. (D32), and Fusarium sp. (D41). Penicillium sp. (code D32) showed significant antioxidant potential activity as an also significant antimicrobial activity with IC50 59,16% and highest zone inhibition against E. coli 13.38 ± 0.25 mm. It is worth considering a further investigation of their bioactive secondary metabolites and isolates the bioactive compound for the antioxidant and antimicrobial agents.
ISSN:1742-6588
1742-6596
DOI:10.1088/1742-6596/1751/1/012059