Estimating The Efficiency Of Phagocytic Neutrophil Cells And Studying Its Risk Factors Among Diabetic Foot Ulcers

• Published in: Journal of physics. Conference series 2021-05, Vol.1900 (1), p.12006
• Main Authors: Baras, M H, Bin-Hameed, E A
• Format: Article
• Language: English
• Subjects: Blood; Diabetes; Diabetes mellitus; Efficiency; Foot diseases; Glucose; Leg ulcers; Physics; Quality; Risk analysis; Ulcers
• ISSN: 1742-6588; 1742-6596
• DOI: 10.1088/1742-6596/1900/1/012006

There are several factors that affect the efficiency of phagocytic activity in diabetic patients. In this study, a significant difference of phagocytosis efficiency showed in diabetic patients and controls (non-diabetic). The means of phagocytic activity were 43.05%, 52.70% and 71.35% for diabetic foot ulcer, diabetes mellitus patients and controls respectively. Age groups, mean blood glucose levels and controlling fasting blood glucose were significant factors effects on phagocytic activity (P-value = 0.022, 0.013 and 0.045) respectively. There was reverse significant correlation between the mean blood glucose and phagocytic activity (P-value = 0.049; r =-0.314). Wagner grade ulcers classified I and II were the most prevalent 30% for both in diabetic foot ulcer patients. And we found that there is a weak negative correlation between the phagocytic activity efficiency and the grades of the classified ulcers (r =-0.323). In this study, we revealed that the efficiency of phagocytic activity was affected by many factors. Level of blood glucose control was the most important factor.