Synthesis of silver nanoparticles coated with bovine serum albumin for application as vaccine carriers

Nanostructured particles represent a viable option for antigen carrier design in new vaccine development. In this research stage, some of the results obtained for the synthesis of silver nanoparticles covered with bovine serum albumin (AgNP-BSA) are presented. The silver nanoparticles were obtained...

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Bibliographic Details
Published in:Journal of physics. Conference series 2022-07, Vol.2315 (1), p.12014
Main Authors: Rodríguez-Calderón, A G, Contreras-García, M E, Nuñez-Anita, R E
Format: Article
Language:English
Subjects:
Antigens
Cattle
Chemical reduction
Light diffraction
Nanoparticles
Photon correlation spectroscopy
Physics
Reducing agents
Serum albumin
Silver nitrate
Sodium citrate
Synthesis
Vaccines
Zeta potential
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Summary:Nanostructured particles represent a viable option for antigen carrier design in new vaccine development. In this research stage, some of the results obtained for the synthesis of silver nanoparticles covered with bovine serum albumin (AgNP-BSA) are presented. The silver nanoparticles were obtained by chemical reduction of silver nitrate (AgNO 3 ) as precursor and sodium citrate (C 6 H 5 Na 3 O 7 ) as reducing agent. The AgNP-BSA were obtained from the wet impregnation method using bovine serum albumin suspension at five different concentrations. The nanostructures were characterized by UV-vis spectroscopy, scanning electron microscopy (SEM), energy dispersive spectroscopy (EDS), X-ray diffraction (XRD), dynamic light scattering (DLS), and zeta potential (ζ).
ISSN:1742-6588
1742-6596
DOI:10.1088/1742-6596/2315/1/012014