Supersymmetric Quantum Mechanics Formalism in a Modeling for Protein Folding

Recently, a mathematical method was developed to analyze the kinetics of the protein folding process, considering it as a diffusion process described by the Fokker-Planck equation and its solution, the time-dependent probability density. This work presents the main points of the methodology, based o...

Full description

Saved in:
Bibliographic Details
Published in:Journal of physics. Conference series 2023-12, Vol.2667 (1), p.12025
Main Authors: Drigo Filho, E, Chahine, J, Araujo, M T, Ricotta, R M
Format: Article
Language:English
Subjects:
Fokker-Planck equation
Folding
Formalism
Free energy
Physics
Proteins
Quantum mechanics
Supersymmetry
Citations: Items that this one cites
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Recently, a mathematical method was developed to analyze the kinetics of the protein folding process, considering it as a diffusion process described by the Fokker-Planck equation and its solution, the time-dependent probability density. This work presents the main points of the methodology, based on the application of the algebraic formalism of Supersymmetric Quantum Mechanics associated with the variational method, to analyze the symmetric tri-stable free energy potential function that describes the unfolded and folded states, as well as an intermediate state of the protein.
ISSN:1742-6588
1742-6596
DOI:10.1088/1742-6596/2667/1/012025