A windowed fourier transform-based method of numerically analyzing phase shifts of SPR sensors

This study presents a simple and reliable method for numerical evaluation of the sensitivity of SPR systems. A Windowed Fourier Transform (WFT) based method is applied to extract shifts of SPR interferogram. By applying the WFT, the frequencies consisting of SPR interferogram are extracted, and phas...

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Bibliographic Details
Published in:Journal of physics. Conference series 2024-03, Vol.2724 (1), p.12047
Main Authors: Peng, Shikang, Wang, Guofu, Liu, Yansheng, Jia, Xiaobo, Zhou, Jin
Format: Article
Language:English
Subjects:
Fourier transforms
Sensors
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Summary:This study presents a simple and reliable method for numerical evaluation of the sensitivity of SPR systems. A Windowed Fourier Transform (WFT) based method is applied to extract shifts of SPR interferogram. By applying the WFT, the frequencies consisting of SPR interferogram are extracted, and phase shifts of relevant frequencies are also obtained. The normalized amplitude of the frequencies larger than 0.35 is regarded as the most prominent frequency. The summation of the phase shifts of the most prominent frequencies is regarded as an index to numerically analyzing phase shifts of SPR sensors. Through this method, the small change in the sensing surface can be monitored. By using a homemade SPR system with the proposed calculation method, it can detect the NaCl solutions ranging from 0.00003% to 0.03% (wt%), indicating its great promise for applications in fields such as medicine, food safety, and biotechnology.
ISSN:1742-6588
1742-6596
DOI:10.1088/1742-6596/2724/1/012047