Protection and sensitization of normal and tumor cells to proton radiation by cerium oxide nanoparticles

Synopsis Cerium oxide nanoparticles are investigated as radioprotectors and radiosensitizers for normal (healthy) and tumor cells for charged particle radiation. Results are presented for cell survival and DNA damage for in-vitro irradiation of normal breast epithelial cells and prostate tumor cells...

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Bibliographic Details
Published in:Journal of physics. Conference series 2015-09, Vol.635 (3), p.32032
Main Authors: Shinpaugh, J L, Swartz, B, Putnam-Evans, C, Das, S, Seal, S
Format: Article
Language:English
Subjects:
Cerium oxides
Charged particles
Epithelium
Nanoparticles
Physics
Proton irradiation
Radiation
Radiation damage
Radiosensitizers
Tumors
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Summary:Synopsis Cerium oxide nanoparticles are investigated as radioprotectors and radiosensitizers for normal (healthy) and tumor cells for charged particle radiation. Results are presented for cell survival and DNA damage for in-vitro irradiation of normal breast epithelial cells and prostate tumor cells by 1.5 - 3.0 MeV protons.
ISSN:1742-6588
1742-6596
DOI:10.1088/1742-6596/635/3/032032