Preliminary study of surface modification of 3D Poly (ɛ - caprolactone) scaffolds by ultrashort laser irradiation

Three - dimensional poly (e- caprolactone) (PCL) scaffolds as suitable biocompatible material for manufacturing tissue replacements are utilized for tissue engineering purposes. The porous structures are fabricated by rapid prototyping method (Bioscaffolder) based on hypodermic dispensing process. T...

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Bibliographic Details
Published in:Journal of physics. Conference series 2016-02, Vol.682 (1), p.12006
Main Authors: Daskalova, A, Bliznakova, I, Iordanova, E, Yankov, G, Grozeva, M, Ostrowska, B
Format: Article
Language:English
Subjects:
Biocompatibility
Biomedical materials
Lasers
Physics
Rapid prototyping
Scaffolds
Tissue engineering
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Summary:Three - dimensional poly (e- caprolactone) (PCL) scaffolds as suitable biocompatible material for manufacturing tissue replacements are utilized for tissue engineering purposes. The porous structures are fabricated by rapid prototyping method (Bioscaffolder) based on hypodermic dispensing process. The consecution of experiments demonstrated the possibility on creation of surface micro formations, applying different laser fluences, at 1 kHz repetition rate for fixed time of exposure 1 sec at 800 nm central wavelength. The combination of both methods offers possibilities for successful production of 3D matrices with modified surfaces. The obtained results of laser - induced surface modifications of PCL demonstrate the potential of the method to microprocess this kind of material for possible applications in regenerative medicine.
ISSN:1742-6588
1742-6596
DOI:10.1088/1742-6596/682/1/012006