Green synthesis of halogenated flavonoids and their pharmacological properties: a mini-review

Halogenated flavonoids have attracted much attention due to their diverse biological activities and potential therapeutic applications. These organic molecules are modified by introducing halogen atoms, such as fluorine, chlorine, bromine, and iodine, which can significantly change their physicochem...

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Bibliographic Details
Published in:IOP conference series. Earth and environmental science 2024-12, Vol.1419 (1), p.012001
Main Authors: Danova, A, Hermawati, E, Mujahidin, D
Format: Article
Language:English
Subjects:
Biological activity
Biological properties
Bromine
Chemical synthesis
Chlorine
Environmental behavior
Flavonoids
Fluorine
Halogenation
Hazardous areas
Hazardous wastes
Iodine
Organic chemistry
Pharmacology
Physicochemical properties
Reagents
Sustainability
Therapeutic applications
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Summary:Halogenated flavonoids have attracted much attention due to their diverse biological activities and potential therapeutic applications. These organic molecules are modified by introducing halogen atoms, such as fluorine, chlorine, bromine, and iodine, which can significantly change their physicochemical properties, affecting biological activity and environmental behavior. As environmental sustainability becomes an increasing concern, eco-synthesis, which involves the design and development of environmentally friendly synthetic pathways, has emerged as a major area of focus in the synthesis of halogenated flavonoids. This approach aims to minimize the use of hazardous reagents and solvents, reduce waste generation and improve overall sustainability. Therefore, this study aims to discuss green halogenation methods and the pharmacological properties of halogenated flavonoids.
ISSN:1755-1307
1755-1315
DOI:10.1088/1755-1315/1419/1/012001