Nanocrystal cellulose as drug excipient in transdermal patch for wound healing: an overview

Wound must be carefully treated to avoid serious infection that needs costly treatment. Method to enhance the recovery of the wound is crucial to have effective wound treatment. One of the technologies in wound treatment is transdermal patch that has the benefits of being non-invasive, easy to handl...

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Bibliographic Details
Published in:IOP conference series. Materials Science and Engineering 2018-03, Vol.334 (1), p.12046
Main Authors: Mohd Zuki, S A, Abd Rahman, N, Abu Bakar, N F
Format: Article
Language:English
Subjects:
Biodegradability
Cellulose
Drug delivery systems
Excipients
Nanocrystals
Wound healing
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Summary:Wound must be carefully treated to avoid serious infection that needs costly treatment. Method to enhance the recovery of the wound is crucial to have effective wound treatment. One of the technologies in wound treatment is transdermal patch that has the benefits of being non-invasive, easy to handle and permits constant drug dosage. In order to obtain a good controlled drug release, drug excipient needs to be investigated. Recently, natural Nanocrystal Cellulose (NCC) which can be synthesized from animal, algae, microorganism or plant has been actively used in drug delivery system as excipient. The application of NCC is advantageous due to its large surface area, biodegradable, non-toxic and abundance source.
ISSN:1757-8981
1757-899X
DOI:10.1088/1757-899X/334/1/012046