Study of the effects of the introduction of heparin on the mechanical properties of poly (glycolide-dl-lactide)

A technology has been developed for producing biodegradable films based on poly (glycolide-lactide) containing heparin. The obtained biodegradable films simulate the coatings of cava filters. The effect of the concentration of introduced heparin and the change in the molecular weight of poly (glycol...

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Bibliographic Details
Published in:IOP conference series. Materials Science and Engineering 2019-04, Vol.525 (1), p.12099
Main Authors: Baikin, A S, Sergienko, K V, Kaplan, M A, Leonov, A V, Kolmakova, A A, Danilova, E A, Shatova, L A, Tsareva, A M, Leonova, Yu O, Ustinova, Yu N, Glinushkin, A.P., Sevostyanov, M A
Format: Article
Language:English
Subjects:
Biodegradability
Coatings
Heparin
Mechanical properties
Plastic properties
Thickness
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Summary:A technology has been developed for producing biodegradable films based on poly (glycolide-lactide) containing heparin. The obtained biodegradable films simulate the coatings of cava filters. The effect of the concentration of introduced heparin and the change in the molecular weight of poly (glycolide-lactide) on the strength and plastic properties, as well as on the thickness of the films obtained, is shown. The possibility of creating coatings with introduced heparin for cava filters with the required mechanical properties is shown.
ISSN:1757-8981
1757-899X
1757-899X
DOI:10.1088/1757-899X/525/1/012099