Production of valuable chemical compounds isolated from plants by endophytic fungi

Natural products have always been an integral part of medical therapy. Many drugs have been developed from natural products mostly derived from plants. For example, the most effective anticancer compounds such as anthracyclines, vinblastine, vincristine, paclitaxel and camptothecins are produced by...

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Bibliographic Details
Published in:IOP conference series. Materials Science and Engineering 2020-04, Vol.823 (1), p.12045
Main Author: Ola, Antonius R B
Format: Article
Language:English
Subjects:
Anticancer properties
Cancer
Chemical compounds
Drugs
Fungi
Natural products
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Summary:Natural products have always been an integral part of medical therapy. Many drugs have been developed from natural products mostly derived from plants. For example, the most effective anticancer compounds such as anthracyclines, vinblastine, vincristine, paclitaxel and camptothecins are produced by plants. However, productions of these highly valuable compounds have threatened the existence of the plants as it requires a large number of materials from plants. This paper highlights the potential and importance of endophytic fungi as the producers of highly valuable compounds as it needs only a small amount of material from plants. For example, anticancer drugs like paclitaxel, vincristine and vinblastine were more commonly found in endophytic fungi than in plants.
ISSN:1757-8981
1757-899X
DOI:10.1088/1757-899X/823/1/012045