Facile green synthesis of ZnO–CuO nanocomposites using areca catechu leaves and their in vitro antidiabetic and cytotoxicity studies

The fabrication and diverse applications of mixed oxides have received immense interest due to numerous prospects for better functional performance in tuning their properties compared to the basic metal oxides. Herein, we report synthesis of ZnO-CuO nanocomposites (NCs) using a simple and green rout...

Full description

Saved in:
Bibliographic Details
Published in:Advances in natural sciences. Nanoscience and nanotechnology 2021-12, Vol.12 (4), p.45018
Main Authors: Shwetha, U R, Latha, M S, Betageri, Virupaxappa S, Pujar, G H, Rajith Kumar, C R, Kiran, M S, Sunita, M S, Gokavi, Nagappa B, Kollur, Shiva Prasad
Format: Article
Language:English
Subjects:
Anticancer properties
antidiabetic activity
Areca catechu
Basic oxides
Biological effects
Catechu
Copper oxides
Cytotoxicity
Diabetes mellitus
Electron microscopy
Fabrication
IC50 value
Metal oxides
Microscopy
Mixed oxides
Nanocomposites
Nanomaterials
Nanotechnology
Scanning electron microscopy
Synthesis
Toxicity
Transmission electron microscopy
X-ray diffraction
Zinc oxide
ZnO–CuO NCs
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:The fabrication and diverse applications of mixed oxides have received immense interest due to numerous prospects for better functional performance in tuning their properties compared to the basic metal oxides. Herein, we report synthesis of ZnO-CuO nanocomposites (NCs) using a simple and green route solution combustion method. The as-prepared ZnO-CuO NCs have been characterised through x-ray diffraction (XRD), energy dispersive x-ray (EDX) with scanning electron microscopy (SEM) and transmission electron microscopy (TEM) techniques. The results revealed that as-prepared ZnO-CuO NCs have spherical and rod-shaped structures with an average size between 10 and 30 nm. Further, ZnO-CuO NCs were tested for antidiabetic and anticancer properties. Amylase inhibition and MTT assays were carried out with different concentrations of NCs. The biological results depicted that the as-prepared nanocomposites exhibited significant cytotoxic effects with IC 50 value of 13.29 μ g mg −1 . These observations further showed that the newly synthesised ZnO–CuO NCs are interesting and promising nanomaterials in pharmaceutical and healthcare sector.
ISSN:2043-6262
2043-6254
2043-6262
DOI:10.1088/2043-6262/ac44a1