The investigation of different cameras for in-beam PET imaging

In situ and in vivo treatment plan verification and beam monitoring as well as dose control during heavy-ion tumour therapy can be performed in principle by measurements of range distributions of beta(+)-emitting nuclei by means of PET techniques. For this purpose the performance of different types...

Full description

Saved in:
Bibliographic Details
Published in:Physics in medicine & biology 1996-02, Vol.41 (2), p.279-296
Main Authors: Pawelke, J, Byars, L, Enghardt, W, Fromm, W D, Geissel, H, Hasch, B G, Lauckner, K, Manfraß, P, Schardt, D, Sobiella, M
Format: Article
Language:English
Subjects:
Beta Particles
Biological and medical sciences
Fluorine Radioisotopes
Humans
Investigative techniques, diagnostic techniques (general aspects)
Medical sciences
Miscellaneous. Technology
Neon
Oxygen Radioisotopes
Photography - instrumentation
Radioisotopes
Radionuclide investigations
Radiotherapy
Sensitivity and Specificity
Tomography, Emission-Computed - instrumentation
Tomography, Emission-Computed - methods
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:In situ and in vivo treatment plan verification and beam monitoring as well as dose control during heavy-ion tumour therapy can be performed in principle by measurements of range distributions of beta(+)-emitting nuclei by means of PET techniques. For this purpose the performance of different types of positron camera as well as the results of in-beam PET experiments using beams of beta(+)-active heavy ions (15O, 17F and 19Ne with energies of 300-500 A MeV) are presented. Following the deduced performance requirements a PET scanner that is designed for clinical use in experimental heavy-ion therapy at GSI Darmstadt has been built. This limited angle tomograph consists of two large-area detector heads based on position sensitive BGO detectors and is predicted to perform the measurement of the end point of a beta(+)-emitting ion beam for the verification of a treatment plan with a precision better than 1 mm. The maximum dose applied in the patient thereby is of the magnitude of 10 mGy.
ISSN:0031-9155
1361-6560
DOI:10.1088/0031-9155/41/2/006