Opto-thermal radiometry for in-vivo nail measurements

We have developed a new method for in-vivo human nail characterization by using opto-thermal transient emission radiometry (OTTER) and condenser-chamber TEWL (trans-dermal water loss) method – AquaFlux. With OTTER, we can measure nail water content, nail water concentration depth profiles, as well a...

Full description

Saved in:
Bibliographic Details
Published in:Journal of physics. Conference series 2010-03, Vol.214 (1), p.012008
Main Authors: Xiao, P, Ciortea, L I, Singh, H, Berg, E P, Imhof, R E
Format: Article
Language:English
Subjects:
Diffusion
Diffusion coefficient
Moisture content
Penetration
Physics
Radiometry
Solvents
Thermal transients
Water loss
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:We have developed a new method for in-vivo human nail characterization by using opto-thermal transient emission radiometry (OTTER) and condenser-chamber TEWL (trans-dermal water loss) method – AquaFlux. With OTTER, we can measure nail water content, nail water concentration depth profiles, as well as topically applied solvent penetration through nail. With AquaFlux, we can measure nail transonychial water loss (TOWL). Combining the water content results with TOWL results, we can get the water diffusion coefficient of nail. Measuring the water diffusion coefficients of nail at different nail water concentration levels can also yield information on how nail diffusion coefficients change with water content. We will present the theoretical background, and experimental results on water concentration depth profile in nail, as well as topically applied solvent penetration through nail.
ISSN:1742-6596
1742-6588
1742-6596
DOI:10.1088/1742-6596/214/1/012008